Medication info
Amlodipine Tablet (Amlodipine Mesylate Monohydrate)

Amlodipine Tablet (Amlodipine Mesylate Monohydrate)

Prescription medicationTabletOral
Ingredient · strength
Amlodipine Mesylate Monohydrate›6.4mg / 1 tablet
Manufacturer / importer
Genewon Science Co., Ltd.
Appearance
White to grayish-white round tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200700835 · Notified 2007.01.22 · Insurance code 671700760

Summary

Main use
Treatment of hypertension and myocardial ischemia (including stable angina, etc.)
Who takes it
Adults
Adult dose
Adults: Administer 5 mg of amlodipine orally once daily. If symptoms do not improve within 2 ∼ 4 weeks, the dose may be increased to a maximum of 10 mg daily according to the patient's response. Adjust the dose appropriately according to symptoms.

Ingredients

Manufacturer
Genewon Science Co., Ltd.

Efficacy & effects

Treatment of hypertension and myocardial ischemia (including stable angina, etc.)

  • Hypertension
  • fixed occlusion of the coronary artery
  • vasospastic contractions of the coronary circulatory system
  • myocardial ischemia
View approved original text

This medication helps in controlling blood pressure related to hypertension and is used to alleviate symptoms of stable angina caused by insufficient blood supply to the myocardium, as well as variant angina caused by vascular spasm. Through these actions, it improves the ischemic state of the heart muscle, alleviating symptoms and aiding in maintaining cardiovascular health.

How to take

Adult dose

Adults: Administer 5 mg of amlodipine orally once daily. If symptoms do not improve within 2 ∼ 4 weeks, the dose may be increased to a maximum of 10 mg daily according to the patient's response. Adjust the dose appropriately according to symptoms.

Precautions

This medication should not be administered to certain patients. For example, it should not be used by individuals who have allergies to this medication or its components, pregnant or breastfeeding women, patients in cardiogenic shock, patients with severe aortic stenosis, patients with unstable angina, patients who have recently suffered a myocardial infarction, and patients with severe liver dysfunction or hypotension. Moreover, patients with very poor kidney function, elderly individuals, acute heart failure patients, patients with severely elevated blood pressure, patients with slightly poor liver function, patients with limited cardiac function, patients with low cardiac reserve, and diabetic patients should use this medication cautiously. When taking this medication, side effects such as warmth and facial flushing, fatigue, edema, palpitations, dizziness, headache, nausea, drowsiness, and ankle edema may occur. Rarely, symptoms such as dry mouth, increased sweating, decreased blood pressure, neurological issues, gastrointestinal problems, skin rashes, and liver dysfunction can also emerge, so immediate consultation with healthcare professionals is required if any abnormal symptoms appear. Abruptly stopping the medication can worsen symptoms; therefore, if discontinuing or adjusting the dosage, it must be done gradually under a physician's guidance. This medication should be avoided with grapefruit juice as it may enhance the hypotensive effect excessively. Additionally, interactions may occur when used with other antihypertension medications, certain antidepressants, nitrates, antiarrhythmic agents, etc., so it is imperative to inform healthcare professionals. For pregnant or breastfeeding women, it is recommended to avoid use as the safety of this medication has not been established. For elderly patients, the blood concentration of this medication may increase, so it should be started at a low dose and taken cautiously. In cases of overdose, there is a risk of severe hypotension, arrhythmias, and shock requiring immediate emergency treatment; since this medication is not removed by hemodialysis, professional treatment is necessary. Finally, this medication should be kept out of reach of children and should not be transferred to another container for safety.

Side effects

Flushing with heat sensation, fatigue, edema, increased frequency of palpitations and angina, dizziness, headache, migraine, weakness, abdominal pain, nausea, dyspepsia, drowsiness, ankle edema, dry mouth, increased sweating, weakness, lethargy, pain, weight gain, weight loss, chills, hypotension, orthostatic hypotension, orthostatic dizziness, peripheral ischemia, vasculitis, syncope, tachycardia, peripheral edema, tension increase, sensory loss, sensory abnormalities, peripheral neuropathy, taste abnormalities, tremors, paralysis, erectile dysfunction, gynecomastia, changes in bowel habits, gastritis, gingival hypertrophy, pancreatitis, vomiting, fullness, loss of appetite, increased appetite, dysphagia, abdominal bloating, hyperglycemia, thirst, elevation of serum cholesterol, elevation of creatine kinase, arthralgia, low back pain, muscle cramps, myalgia, increased skeletal muscle tone, arthrosis, single contraction, ataxia, back pain, leukopenia, thrombocytopenia, insomnia, mood changes, sexual dysfunction, abnormal dreams, depersonalization, apathy, restlessness, amnesia, sensitivity, depression, anxiety, confusion, fear, discomfort, cough, dyspnea, rhinitis, epistaxis, hair loss, purpura, skin discoloration, urticaria, photosensitivity reaction, rash, erythematous rash, papular rash, cool and moist skin, capillary dilation, rash, itching, angioedema, toxic epidermal necrolysis, tinnitus, visual disturbances, conjunctivitis, diplopia, eye pain, dry eyes, olfactory abnormalities, gustatory abnormalities, visual impairment, increased frequency of urination, urination disorders, nocturia, polyuria, dysuria, hepatitis, jaundice, elevated liver enzyme levels, itching, rash, angioedema, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, myocardial infarction, arrhythmia, chest pain, decreased blood pressure, sinus node block, atrioventricular block, abdominal discomfort, precordial pain, diarrhea, loose stools, constipation, skin erythema, papular maculopapular rash, heavy sensation, heat sensation, decreased glucose tolerance, weakness, systemic hypotension, flushing, headache, reflex tachycardia, cardiac arrhythmia, blood circulation abnormalities, shock, unconsciousness, coma, non-cardiogenic pulmonary edema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that does not allow light exposure. Additionally, it is recommended to store it at room temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White to grayish-white round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.