Medication info
Amlodipine 5 mg (Amlodipine Besylate Hydrate)

Amlodipine 5 mg (Amlodipine Besylate Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Amlodipine Mesylate Monohydrate›6.4mg / 1 tablet
Manufacturer / importer
IlYang Pharmaceutical Co., Ltd.
Appearance
White to pale yellow round tablets
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 200700603 · Notified 2007.01.16 · Insurance code 641702980

Summary

Main use
Treatment of hypertension and myocardial ischemia (e.g., stable angina)
Who takes it
Adults
Adult dose
Adults: Administer 5 mg orally once daily as amlodipine. If symptoms do not improve within 2 ∼ 4 weeks, the dose may be increased, depending on the patient's response, up to a maximum of 10 mg once daily. Adjust the dose as appropriate according to symptoms.

Ingredients

Manufacturer
IlYang Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of hypertension and myocardial ischemia (e.g., stable angina)

  • Hypertension
  • fixed occlusion of the coronary artery
  • vasoconstriction of coronary vessels
  • myocardial ischemia
View approved original text

This medication is used to control hypertension and to treat myocardial ischemia caused by stable angina due to narrowed coronary arteries that limit blood supply to the heart and variant angina caused by vascular spasms.

How to take

Adult dose

Adults: Administer 5 mg orally once daily as amlodipine. If symptoms do not improve within 2 ∼ 4 weeks, the dose may be increased, depending on the patient's response, up to a maximum of 10 mg once daily. Adjust the dose as appropriate according to symptoms.

Precautions

This medication should not be used in certain patients. For example, it should not be given to individuals who are allergic to this drug or any of its ingredients, pregnant or nursing women, or patients with severe heart issues or liver dysfunction. Also, patients with severely impaired kidney function, elderly individuals, and those with acute heart failure should use this medication with special caution. These patients should take it carefully according to their doctor's instructions. While taking this drug, side effects such as warmth, flushing, fatigue, edema, dizziness, headache, and nausea may occur. If severe hypotension, heart problems, allergic reactions, or liver dysfunction symptoms appear, consult a doctor immediately. Sudden discontinuation of this medication may worsen symptoms; therefore, it is essential to follow a doctor's instruction when stopping or adjusting the dose. When taking this medication, consume it with plenty of water, and be cautious when driving or operating dangerous machinery as dizziness or drowsiness may occur due to its antihypertensive effects. This drug may interact with other medications, so it is advisable to avoid taking it with grapefruit juice, and caution is required when taken with specific antibiotics, antihypertensives, antidepressants, etc. In cases of pregnancy or breastfeeding, it is recommended to avoid use as its safety has not been established. Safety in children has also not been confirmed. Elderly patients may have higher concentrations of this medication in their bodies, so starting with a lower dose and observing the condition is recommended. In case of overdose, severe hypotension, arrhythmias, or shock may occur, so seek medical attention immediately for appropriate treatment. Finally, this medication should be kept out of reach of children, and it is safe not to transfer it to other containers.

Side effects

  • Flushing accompanied by heat sensation
  • increased frequency of fatigue
  • edema
  • palpitations
  • angina
  • dizziness
  • headache
  • migraine
  • weakness
  • abdominal pain
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  • nausea
  • dyspepsia
  • drowsiness
  • ankle edema
  • dry mouth
  • increased sweating
  • weakness
  • lethargy
  • pain
  • weight gain
  • weight loss
  • chills
  • hypotension
  • postural hypotension
  • postural dizziness
  • peripheral ischemia
  • vasculitis
  • fainting
  • tachycardia
  • peripheral edema
  • tension increase
  • sensory loss
  • paresthesia
  • peripheral neuropathy
  • taste disturbance
  • tremor
  • paralysis
  • erectile dysfunction
  • gynecomastia
  • change in bowel habits
  • gastritis
  • gingival hypertrophy
  • pancreatitis
  • vomiting
  • feeling of fullness
  • loss of appetite
  • increased appetite
  • dysphagia
  • abdominal bloating
  • hyperglycemia
  • thirst
  • elevated serum cholesterol
  • increased creatine kinase
  • arthralgia
  • low back pain
  • muscle cramps
  • myalgia
  • increased skeletal muscle tone
  • arthrosis
  • single contraction
  • ataxia
  • back pain
  • leukopenia
  • thrombocytopenia
  • insomnia
  • mood changes
  • sexual dysfunction
  • abnormal dreams
  • depersonalization
  • apathy
  • anxiety
  • amnesia
  • sensitivity
  • depression
  • unease
  • confusion
  • fear
  • discomfort
  • cough
  • dyspnea
  • rhinitis
  • nosebleed
  • hair loss
  • purpura
  • skin discoloration
  • urticaria
  • photosensitivity reactions
  • rash
  • erythematous rash
  • papular rash
  • cold and damp skin
  • capillary dilation
  • dermatitis
  • itching
  • vascular edema
  • toxic epidermal necrolysis
  • tinnitus
  • visual disturbances
  • conjunctivitis
  • diplopia
  • eye pain
  • dry eyes
  • olfactory disturbances
  • taste disturbances
  • visual acuity decrease
  • increased urinary frequency
  • urination disorders
  • nocturia
  • polyuria
  • painful urination
  • hepatitis
  • jaundice
  • elevation of liver enzyme levels
  • itching
  • erythema multiforme
  • exfoliative dermatitis
  • skin and mucous membrane syndrome
  • myocardial infarction
  • arrhythmia
  • chest pain
  • hypotension
  • sinoatrial block
  • atrioventricular block
  • abdominal discomfort
  • precordial pain
  • diarrhea
  • loose stools
  • constipation
  • skin erythema
  • maculopapular rash
  • heaviness
  • heat sensation
  • decreased glucose tolerance
  • weakness
  • systemic hypotension
  • flushing
  • headache
  • heart rhythm disturbances
  • blood circulation abnormalities
  • shock state
  • unconsciousness
  • coma
  • non-cardiogenic pulmonary edema

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a tightly sealed container that blocks light. Additionally, it should be stored at room temperature, between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

White to pale yellow round tablets

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.