Amlokan Tablets (Amlodipine Mesylate Hydrate)

Adult dose

Adults: Administer 5 mg of amlodipine orally once daily. If symptoms do not improve within 2 ∼ 4 weeks, the dose may be increased to a maximum of 10 mg once daily according to the patient’s response. Adjust the dose as appropriate according to symptoms.

This medication should not be used in certain patients. It should not be administered to individuals allergic to this medication or similar components, pregnant or nursing women, and patients with severe heart problems or liver dysfunction. Additionally, it should not be used in patients in shock or those with severe hypotension. This medication should be used with caution in patients with severely impaired kidney function, the elderly, patients with heart failure, patients with moderate to mild liver dysfunction, and diabetic patients. Such patients may experience unpredictable effects of the medication; hence, close monitoring by healthcare professionals is necessary. Adverse effects such as flushing, fatigue, edema, dizziness, headache, and dyspepsia may occur while taking this medication. If there is an exacerbation of symptoms like tachycardia or angina, immediate consultation with healthcare professionals is necessary. Rarely, allergic reactions, liver function abnormalities, and blood dyscrasias have been reported; thus, it is important to inform healthcare professionals of any unusual symptoms. Discontinuing this medication abruptly may worsen symptoms, so it should not be stopped without a doctor's direction. It should be taken with sufficient water, and caution is advised when driving or performing hazardous tasks due to possible dizziness or drowsiness. This medication can interact with other drugs, so it is imperative to inform healthcare professionals about any current medications. Notably, grapefruit juice may excessively enhance the effects of this medication, so it is advisable not to take them together. Pregnant or nursing women are advised not to use this medication, and it is recommended to discontinue breastfeeding while on this medication. Safety for pediatric use has not been established; therefore, it should be used cautiously in children, and the elderly should start at a low dose to monitor potential accumulation of the drug. In cases of overdose, severe hypotension, cardiac problems, and shock may occur, requiring immediate medical attention, and blood dialysis may not be effective. This medication should be stored out of reach of children, and transferring it to another container is not recommended as it may compromise quality.

Flushing with heat sensation, fatigue, swelling, increased frequency, duration, and degree of palpitations and angina, dizziness, headache, migraine, weakness, abdominal pain, nausea, dyspepsia, drowsiness, dry mouth, increased sweating, weakness, lethargy, pain, weight gain, weight loss, chills, hypotension, orthostatic hypotension, orthostatic dizziness, peripheral ischemia, vasculitis, syncope, tachycardia, peripheral edema, tension increase, sensory decrease, sensory disturbances, peripheral neuropathy, taste disturbances, tremor, paralysis, erectile dysfunction, gynecomastia, changes in bowel habits, gastritis, gingival hypertrophy, pancreatitis, vomiting, fullness, loss of appetite, increased appetite, difficulty swallowing, abdominal bloating, hyperglycemia, thirst, elevated serum cholesterol, elevated creatine kinase, arthralgia, low back pain, muscle cramps, myalgia, increased skeletal muscle tone, arthritis, single contraction, ataxia, back pain, leukopenia, thrombocytopenia, insomnia, mood changes, sexual dysfunction, abnormal dreams, depersonalization, apathy, anxiety, memory loss, sensitivity, depression, anxiety, confusion, fear, discomfort, cough, dyspnea, rhinitis, epistaxis, hair loss, purpura, skin discoloration, urticaria, photosensitivity reaction, rash, erythematous rash, papular rash, cool damp skin, capillary dilation, urticaria, itching, angioedema, toxic epidermal necrolysis, tinnitus, visual disturbances, conjunctivitis, diplopia, eye pain, dry eyes, olfactory disturbances, taste disturbances, decreased vision, increased urinary frequency, urinary disorders, nocturia, polyuria, dysuria, hepatitis, jaundice, elevated liver enzyme levels, itching, angioedema, polymorphous erythema, exfoliative dermatitis, Stevens-Johnson syndrome, myocardial infarction, arrhythmia, chest pain, hypotension, sinoatrial block, atrioventricular block, abdominal discomfort, precordial pain, diarrhea, loose stools, constipation, skin erythema, papular urticarial rash, heaviness, heat sensation, decreased glucose tolerance, weakness, systemic hypotension, flushing, headache, reflex tachycardia, cardiac arrhythmia, cardiovascular blood circulation abnormalities, shock state, unconsciousness, coma, non-cardiogenic pulmonary edema

This medication is sensitive to light and should be stored in a container that shields from light. Additionally, it should be stored at room temperature between 1 to 30 degrees Celsius.

Appearance

White to grayish-white round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle