Medication info
Losartan Potassium and Hydrochlorothiazide Plus F Tablet

Losartan Potassium and Hydrochlorothiazide Plus F Tablet

Prescription medicationTablet경구
Ingredient · strength
Losartan Potassium›100mg / 1 tabletHydrochlorothiazide›25mg / 1 tablet
Manufacturer / importer
(주)유한양행
Appearance
Light yellow oval film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 200700468 · Notified 2007.01.11 · Insurance code 642100320

Summary

Main use
Improvement in blood pressure control when monotherapy for hypertension is insufficient
Who takes it
Adults · Children
Adult dose
The standard dosage for adults is 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide once daily. A dosage exceeding 100 mg of losartan potassium and 25 mg of hydrochlorothiazide per day is undesirable. 1. For patients whose blood pressure is not controlled with monotherapy of losartan or hydrochlorothiazide: Start with 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide once daily.
Child dose
Due to lack of experience in pediatric and adolescent populations, the combination of losartan and hydrochlorothiazide is not administered to children and adolescents.

Ingredients

Manufacturer
(주)유한양행

Efficacy & effects

Improvement in blood pressure control when monotherapy for hypertension is insufficient

  • Hypertension
View approved original text

This medication is used for patients with hypertension who have difficulty controlling their blood pressure with monotherapy. It helps to effectively lower blood pressure, reducing the risk of cardiovascular disease.

How to take

Adult dose

The standard dosage for adults is 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide once daily. A dosage exceeding 100 mg of losartan potassium and 25 mg of hydrochlorothiazide per day is undesirable. 1. For patients whose blood pressure is not controlled with monotherapy of losartan or hydrochlorothiazide: Start with 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide once daily.

Child dose

Due to lack of experience in pediatric and adolescent populations, the combination of losartan and hydrochlorothiazide is not administered to children and adolescents.

Precautions

This medication should not be used during pregnancy, particularly in the second and third trimesters, as it can cause serious harm to the fetus. It should be discontinued immediately upon confirmation of pregnancy, and patients should follow their physician's instructions to ensure the health of the fetus and newborn. This medication should not be administered to patients with certain conditions or known hypersensitivity. For instance, patients with severely impaired kidney function or significant liver dysfunction, as well as those allergic to specific medications, should not use it. Patients with severely low blood pressure or issues with renal blood vessels, as well as those with electrolyte imbalances, should use this medication with caution. Elderly patients or those with certain chronic illnesses also require careful consideration. While taking this medication, dizziness, drowsiness, and symptoms of low blood pressure may occur, so caution is advised when driving or operating machinery. This medication may affect potassium levels in the blood, so potassium supplements or medications containing potassium should not be taken without consulting a physician. The hydrochlorothiazide component can cause electrolyte imbalances; hence, regular blood tests should be conducted to monitor electrolyte status. Additionally, this medication may cause photosensitivity; precautions should be taken to avoid sun exposure and protect the skin. If sudden changes in vision or eye pain occur while taking this medication, immediate consultation with a healthcare provider is necessary, and it should be discontinued if severe side effects are suspected. In case of overdose, symptoms such as low blood pressure or irregular heartbeat may occur, so adhering to the prescribed dosage is critical, and any unusual symptoms should prompt an immediate visit to a medical institution. Pregnant or nursing individuals should consult a physician before taking this medication, and caution is necessary during breastfeeding as this medication may affect the baby. There is insufficient experience with this medication in children and adolescents, so it is recommended not to administer it to this age group. When taking other medications concurrently, interactions may occur, so it is essential to inform and consult with healthcare professionals regarding current medications.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, mucosal pain in mouth/eyes, wheezing or difficulty breathing, asthma attacks, breathing abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination changes

Mild side effects

Abdominal pain, edema/swelling, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory infection, weakness/fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, palm skin peeling phenomenon, hemolysis, chest pain, facial swelling, fever, orthostatic hypotension, fainting, angina, arrhythmia (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular accident, hypotension, myocardial infarction, secondary atrioventricular block, loss of appetite, constipation, toothache, oral complaints

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and should be stored in a dark place, with a temperature maintained between 1 to 30 degrees Celsius at room temperature. Proper storage will help maintain the effectiveness of the medication and ensure safe usage.

Appearance and packaging

Appearance

Light yellow oval film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.