Pyridazole Tablet 20mg (Rabeprazole Sodium)

Adult dose

The usual dosage for adults is 10 mg orally once daily of Rabeprazole Sodium. Depending on symptoms, 20 mg may be administered orally once daily. Treatment duration is up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease, 10 mg or 20 mg is administered orally once daily for 4 to 8 weeks. If untreated, an additional 8 weeks of 10 mg or 20 mg may be given.

This drug should not be used in patients who are allergic to certain ingredients or benzimidazole derivatives. Also, when used in combination with amoxicillin or clarithromycin for the eradication of Helicobacter pylori, it should not be administered if the patient is allergic to those antibiotics. Patients taking specific heart-related medications or antivirals, as well as pregnant or breastfeeding women, should not use this drug. Patients with liver disease, elderly patients, or those with a history of drug allergies should use this drug cautiously. This drug contains specific colorant ingredients, which may require caution in individuals allergic to those components. If any hypersensitivity reactions such as rash or itching occur during use, discontinuation should be immediate. Regular blood tests are required as there may be changes in red blood cell or white blood cell counts. Liver function tests should also be conducted regularly as signs of liver function abnormalities may occur. Various adverse reactions, including heart-related symptoms or changes in blood pressure, gastrointestinal issues, and neurological symptoms, have been reported; therefore, caution is required if symptoms occur. Respiratory symptoms such as pneumonia or difficulty breathing may occur, and if any unusual signs are present, immediate consultation with a healthcare professional is necessary. Side effects such as myalgia, arthralgia, skin rashes, vision abnormalities, and urinary tract problems may occur. Long-term use may increase the risk of osteoporosis and fractures; hence caution is needed for prolonged treatment. Hypomagnesemia may rarely occur, necessitating periodic checks of magnesium levels when taken for a long time or in combination with certain medications. This drug strongly suppresses gastric acid secretion, which may slightly increase the risk of bacterial infections in the gastrointestinal tract. Caution is advised when driving or operating machinery, as drowsiness or dizziness may occur. There may be drug interactions, so always consult with a healthcare professional regarding concomitant medications, especially when used with antibiotics, antivirals, and anticoagulants. This drug should not be used during pregnancy or breastfeeding, and its safety has not been established. Elderly patients should be particularly careful due to a higher potential for side effects arising from reduced liver function. Safety in children has not been established, and its use is not recommended. The tablet should be swallowed whole without chewing or crushing, and it should be stored out of reach of children. No specific antidote exists for overdose; appropriate treatment should be provided based on symptoms. Long-term use may affect the absorption of vitamin B12, necessitating periodic checks. Symptoms of autoimmune diseases such as lupus erythematosus may appear in the skin or systemically; any unusual symptoms should be reported to healthcare professionals immediately. It is important to inform physicians about this drug before any specific tumor marker tests, as it may affect those tests. Serious kidney conditions such as acute interstitial nephritis may occur, and if any kidney-related symptoms develop, discontinuation should be immediate.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, fulminant hepatitis, liver dysfunction, jaundice, myocardial infarction, loss of consciousness, angina, pulmonary embolism, ventricular tachycardia, thrombophlebitis, ventricular tachycardia, hemorrhagic diarrhea, hepatic encephalopathy, seizures, dizziness, confusion, disorientation, consciousness disturbance, vision abnormalities, paralysis, acute interstitial nephritis, renal failure due to acute interstitial nephritis, anaphylaxis, shock

Mild side effects

• Occasional rash
• hives
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia

This drug should be stored in a tightly sealed container to prevent exposure to air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. This helps to preserve the drug's effectiveness and prevent degradation.

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu×2)