Medication info
Rabeprazole Sodium 20 mg Tablet

Rabeprazole Sodium 20 mg Tablet

Prescription medicationTablet경구
Ingredient · strength
Rabeprazole Sodium›20mg / 1 tablet
Manufacturer / importer
(주)파마킹
Appearance
Light yellow round enteric-coated tablet
Packaging
28 tablets/PTP (28 tablets/PTP×1)
Approval status
Active

MFDS item code 200611091 · Notified 2006.11.20 · Insurance code 652300110

Summary

Main use
Symptom relief of peptic ulcer and gastroesophageal reflux disease and effectiveness in combination with antibiotics
Who takes it
Adults · Children
Adult dose
Gastric ulcer, duodenal ulcer: Administer 10 mg orally once daily, and if necessary, can increase to 20 mg once daily depending on symptoms. Typically, treatment lasts up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If untreated, an additional 8-week course of 10 mg or 20 mg twice daily can be given.
Child dose
Safety in children has not been established.

Ingredients

Manufacturer
(주)파마킹

Efficacy & effects

Symptom relief of peptic ulcer and gastroesophageal reflux disease and effectiveness in combination with antibiotics

  • Gastric ulcer
  • duodenal ulcer
  • erosive gastroesophageal reflux disease
  • ulcerative gastroesophageal reflux disease
  • gastroesophageal reflux disease
  • gastrointestinal ulcer caused by Helicobacter pylori infection
  • Zollinger-Ellison syndrome
View approved original text

This medication is effective for the treatment of gastric and duodenal ulcers, and is also used for symptom relief of gastroesophageal reflux disease and long-term maintenance therapy. It is used in combination with antibiotics for patients with digestive tract ulcers caused by Helicobacter pylori infection. It is also applicable for conditions of excessive gastric acid secretion, such as Zollinger-Ellison syndrome. In summary, it helps in the treatment and symptom improvement of various gastric and esophageal diseases.

How to take

Adult dose

Gastric ulcer, duodenal ulcer: Administer 10 mg orally once daily, and if necessary, can increase to 20 mg once daily depending on symptoms. Typically, treatment lasts up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If untreated, an additional 8-week course of 10 mg or 20 mg twice daily can be given.

Child dose

Safety in children has not been established.

Precautions

This medication should not be used in patients with allergies to certain components or who have experienced hypersensitivity reactions. Caution is required in patients with allergies to penicillin or macrolide antibiotics, especially when used in combination during Helicobacter pylori eradication therapy. It is safer for pregnant or breastfeeding women to avoid this medication. Patients with compromised liver function or the elderly may experience more severe side effects, so use with caution is necessary. If allergic symptoms such as skin rash or itching occur during medication, discontinue immediately and consult a doctor. It is important to have regular blood tests or liver function tests to monitor for any abnormal signs. Various side effects may occur in multiple body systems, including the heart, digestive system, and nervous system, so any symptoms that arise should be reported immediately. Long-term use may increase the risk of fractures due to osteoporosis, and bone density tests should be considered if necessary. Hypomagnesemia may occur rarely, so magnesium levels in the blood should be periodically monitored when used long-term or with certain medications. This drug strongly inhibits gastric acid secretion, which may slightly increase the risk of bacterial infections in the stomach; if symptoms like diarrhea persist, consult a doctor. Caution is needed for drowsiness or other symptoms when driving or operating machinery. Interactions may occur when taken with other medications, so inform healthcare providers of all medications being taken. Do not chew or crush this medication; it should be swallowed whole in tablet form, and kept out of the reach of children. It is recommended not to use in children, as clinical safety has not been established. There is no specific antidote for overdose, requiring treatment based on symptoms and supportive therapy.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, decreased urine output

Mild side effects

  • Rash
  • itching
  • decrease in red blood cells
  • decrease in white blood cells
  • increase in white blood cells
  • increase in eosinophils
  • increase in neutrophils
  • decrease in lymphocytes
  • anemia
  • petechia
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  • lymphadenopathy
  • hypochromic anemia
  • pancytopenia
  • agranulocytosis
  • thrombocytopenia
  • hemolytic anemia
  • increased ALT
  • increased AST
  • increased ALP
  • increased γ-GTP
  • increased LDH
  • increased total bilirubin
  • hypertension
  • myocardial infarction
  • ECG abnormalities
  • migraine
  • syncope
  • angina
  • blockade
  • palpitations

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. When stored, it's best to keep it at room temperature, between 1 to 30 degrees Celsius. It is advisable to avoid extremely hot or cold places.

Appearance and packaging

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets/PTP (28 tablets/PTP×1)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.