Pariazole 10 mg (Rabeprazole Sodium)

Adult dose

Gastric ulcer, duodenal ulcer: Typically, the oral dose for adults is 10 mg of rabeprazole sodium once daily. Depending on symptoms, it may be increased to 20 mg once daily. Generally, it is administered for up to 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once daily for 4 to 8 weeks. If untreated, an additional 8 weeks of treatment may be needed at 10 mg. For the relief of symptoms of gastroesophageal reflux disease: 10 mg once daily. If symptoms are not controlled after 4 weeks, further consultation is necessary. After symptoms resolve, on-demand therapy with 10 mg once daily may be used to control any symptoms that subsequently appear. Long-term maintenance therapy for gastroesophageal reflux disease: Depending on the patient, oral doses of 10 mg or 20 mg once daily. Helicobacter pylori eradication: Patients infected with Helicobacter pylori should undergo eradication therapy. Combination therapy of this medication 20 mg with clarithromycin 500 mg and amoxicillin 1 g taken twice daily for 7 days is recommended. Zollinger-Ellison syndrome: The recommended initial dose for adults is 60 mg once daily. The dosage can be adjusted based on individual patient needs up to 120 mg per day. Doses up to 100 mg can be given once daily, while 120 mg should be split into 60 mg taken twice daily. Patients with Zollinger-Ellison syndrome have been treated with this medication for up to 1 year.   Caution for patients with liver dysfunction Adverse reactions related to hepatic encephalopathy have been reported in patients with liver cirrhosis. Therefore, administration should be done cautiously.   Caution for children Safety has not been established for pediatric use.   Caution for elderly patients Administer cautiously as they often have impaired liver function.

Child dose

Safety has not been established for pediatric use.

This medication should not be used in patients who have a history of allergy or hypersensitivity to specific ingredients. Caution is needed when used with certain antibiotics due to the potential for hypersensitivity reactions. It is safest for pregnant or breastfeeding women to avoid taking this medication. Patients with impaired liver function or the elderly may experience side effects, so administration should be done cautiously. While taking this medication, various side effects such as skin rash, itching, blood abnormalities, liver function abnormalities, heart issues, gastrointestinal symptoms, and neurological abnormalities may occur, and immediate consultation with a healthcare professional is required if symptoms appear. This medication reduces gastric acid secretion, so long-term use may increase the risk of bone fractures and can cause hypomagnesemia, requiring regular monitoring. Additionally, there may be a slight increase in the risk of gastrointestinal bacterial infections, so if diarrhea persists, consultation with a physician is recommended. Caution is also necessary when driving or operating machinery, as drowsiness may occur. Due to potential interactions with other medications, any currently taken medications should be disclosed to a healthcare professional, especially when used in conjunction with antibiotics or antiviral medications. This medication should not be chewed or crushed; it should be swallowed whole and stored out of reach of children. In case of overdose, there are no specific antidotes, and appropriate treatment should be given based on the symptoms. For long-term use, regular blood tests and liver function tests are important to check for abnormalities.

Serious side effects

• Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions
• Severe rash with high fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, severe skin adverse reactions
• Difficulty or trouble breathing, asthma attacks, cough + respiratory abnormalities with fever
• Yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice)
• Sudden and very severe headache, lightning-like pain

Mild side effects

• Occasional rash
• hives
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia

This medication should be stored in a tightly sealed container to protect it from air or moisture. Additionally, it is best stored at room temperature between 1°C and 30°C. Avoid storing in excessively hot or cold conditions.

Appearance

Yellowish round enteric-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2)