Rabenix Tablet 20 mg (Rabeprazole Sodium)

Adult dose

Gastric ulcer, duodenal ulcer: Typically, 10 mg is administered orally once a day, with the possibility of increasing to 20 mg once a day based on symptoms. Treatment duration is generally up to 8 weeks for gastric ulcers and up to 6 weeks for duodenal ulcers. Erosive or ulcerative gastroesophageal reflux disease: Administer 10 mg or 20 mg once a day for 4 to 8 weeks. If symptoms persist after 8 weeks of treatment, an additional 8 weeks of 10 mg or 20 mg may be given.

This medication should not be administered to patients with specific allergic reactions. Particularly, it should not be used by individuals who are hypersensitive to this drug or its components, or to benzimidazole derivatives in the past. Additionally, when used in conjunction with penicillin-based antibiotics or macrolide antibiotics for the eradication of Helicobacter pylori, it should not be used if there is an allergy to those antibiotics. Patients taking certain medications that can cause serious side effects when used concurrently with this medication should also avoid use, and it is safer not to use this drug for pregnant or breastfeeding women. Patients with impaired liver function or the elderly should be cautious when using this medication, and those with a history of drug hypersensitivity should be administered with care. If symptoms of hypersensitivity such as rash, hives, or itching occur during the use of this medication, it should be discontinued immediately. Routine blood tests are necessary as changes in red or white blood cell counts may occur, and it is recommended to periodically check liver function as well. Various adverse reactions such as cardiac problems, gastrointestinal symptoms, neurological issues, respiratory problems, muscle pain, and skin rash have been reported; therefore, consultation with medical personnel should occur if these symptoms arise. Long-term use of this medication may increase the risk of fractures and can lead to hypomagnesemia, so magnesium levels should be monitored and supplemented as necessary. This medication suppresses gastric acid secretion, which can promote bacterial growth in the gastrointestinal tract; thus, if diarrhea persists or worsens, the possibility of Clostridium difficile infection should be considered. Caution is necessary as drowsiness may occur when driving or operating machinery. This medication may interact with certain drugs; therefore, if taking other medications, it is essential to inform healthcare providers. It is safer not to use this medication during pregnancy or breastfeeding, and safety in children is not established. In cases of overdose, as there is no specific antidote, treatment and supportive therapy according to symptoms are necessary. This medication should not be chewed or crushed but should be swallowed whole. Keep out of reach of children, and do not transfer to another container. Long-term use of this medication may lead to vitamin B12 absorption disorders, so nutritional status should be monitored if necessary. Autoimmune diseases such as skin or systemic lupus erythematosus may present, so if relevant symptoms occur, consult a medical professional immediately. During the administration of this medicine, liver and kidney function, as well as blood status, should be regularly monitored, and if any abnormal signs are found, the treatment should be stopped and appropriate action taken.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, paleness, fulminant hepatitis, liver dysfunction, jaundice, headache (sudden and very severe, thunderclap headache), seizures, confusion, vision changes, paralysis, significantly reduced urine output, generalized severe edema, increased blood pressure, anaphylaxis, shock, malaise, sudden cardiac death, coma, hyperammonemia, rhabdomyolysis, disorientation, delirium, angioedema, hypomagnesemia

Mild side effects

• Rash
• hives
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. It is best stored at room temperature, between 1 to 30 degrees Celsius. Avoid storing in excessively hot or cold places to help maintain the drug's effectiveness.

Appearance

Pale yellow, round enteric-coated tablet

Package unit

28 tablets/PTP