NovaSc 5 mg Tablet (Amlodipine Besilate)

Adult dose

For amlodipine, the oral dosage is 5 mg once daily, and it can be increased to a maximum of 10 mg per day depending on the patient's response. Adjustments should be made according to age and symptoms.

Child dose

The oral dosage of amlodipine for effective blood pressure lowering is 2.5 mg to 5 mg once daily. The dosage exceeding 5 mg per day in pediatric patients has not been studied.

This medication is a dihydropyridine calcium channel blocker that lowers blood pressure and reduces the burden on the heart. This medication should not be used in patients with hypersensitivity, nursing mothers, patients with severe liver dysfunction, patients with aortic stenosis, and patients in a state of shock. In addition, it should be used cautiously in patients with severe hypotension, those requiring dialysis due to renal failure, elderly patients, and women who are pregnant or may become pregnant. Side effects such as flushing, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea may occur while taking this medication. Rarely, symptoms such as hypotension, vasculitis, neurological abnormalities, erectile dysfunction, gynecomastia, dyspepsia, liver function abnormalities, and skin rashes may appear, so if any abnormal symptoms occur, immediate consultation with a doctor is advised. In patients with heart failure or impaired liver function, the effects and side effects of this medication may be more severe, so it should be used with caution. This medication can be used with other antihypertensives, diuretics, beta-blockers, etc., but it is advisable to avoid taking it with grapefruit juice as it may excessively enhance the blood pressure-lowering effect. Particularly, the risk of hypotension may increase when used in conjunction with certain antibiotics or other medications, so it is essential to consult a doctor or pharmacist about other medications being taken. Women who are pregnant or nursing are advised to avoid using this medication as its safety has not been established, and during nursing, it is recommended to discontinue breastfeeding while taking the medication. In children, it can only be used in those aged 6 years and older, and its safety and efficacy have not been established in children under 6 years. In cases of overdose, severe hypotension and tachycardia may occur, requiring immediate emergency treatment and appropriate measures such as calcium gluconate administration. This medication is known not to significantly affect driving or operating machinery, but caution is advised if dizziness or drowsiness occurs.

Serious side effects

• Hives
• severe swelling (edema)
• severe allergic reactions
• toxic epidermal necrolysis
• hepatitis
• jaundice
• liver abnormalities
• angioedema
• polymorphic erythema
• severe adverse skin reactions

Mild side effects

• Flushing
• fatigue
• swelling
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly closed container to prevent contact with air and moisture, and the storage temperature should be kept between 1 degree and 30 degrees Celsius at room temperature. Storing it this way helps maintain the medication's effectiveness and prevents deterioration.

Appearance

White octagonal tablet

Package unit

30 tablets (10 tablets/blister x 3), 500 tablets/bottle