Losanin Plus Tablet

Adult dose

Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg, once daily 1 tablet. If blood pressure is not controlled, the dose can be increased up to a maximum of Losartan Potassium 100 mg / Hydrochlorothiazide 25 mg, once daily 1 tablet after 3 weeks of administration. This medication can be initiated when blood pressure is not controlled by monotherapy with Losartan or Hydrochlorothiazide. It can be administered without regard to meals.

Child dose

There is no experience of use in children and adolescents (under 18 years), so it should not be administered.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately if pregnancy is confirmed. This medication should not be administered to certain patients, such as those who are allergic to this drug or its components, have severe renal impairment, liver disorders, are pregnant, or have specific electrolyte disturbances. Patients with hypotension or renal function issues should use this medication with extra caution, as blood pressure may drop too low or renal function may worsen, requiring regular monitoring. This medication may alter potassium levels in the blood, so expert consultation is necessary if taken with potassium supplements or other medications containing potassium. Due to the hydrochlorothiazide component, electrolyte imbalance may occur, and it is important to regularly monitor electrolyte status through blood tests. Dizziness or drowsiness may occur during treatment, so caution is needed when driving or operating machinery. Additionally, exposure to sunlight while taking this medication may increase the risk of skin cancer, so regular use of sunscreen and skin examinations are recommended. If any unusual symptoms or side effects occur during use, immediate consultation with healthcare professionals is necessary, especially if blood pressure drops too low or severe allergic reactions, skin rashes, or breathing difficulties arise, which require immediate action. This medication is not recommended for use in children or adolescents due to insufficient experience in this population. Finally, this medication should be stored in its original container and kept out of reach of children.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, angioedema (laryngeal/glottic edema leading to airway obstruction, swelling of face/lips/pharynx/tongue), chest tightness, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, seizures, altered consciousness, visual disturbances, paralysis.

Mild side effects

Abdominal pain, swelling/edema, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory infection, weakness/fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, angioedema (swelling of lips and eyelids, facial rash), chest pain, facial swelling, fever, orthostatic hypotension, fainting, angina, arrhythmias (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular accident, hypotension, myocardial infarction, secondary atrioventricular block, loss of appetite, constipation

This medication is sensitive to light, so it should be stored in a light-protective, tightly closed container. The storage temperature should be maintained between 1 degree and 30 degrees Celsius, avoiding extremely hot or cold environments.

Appearance

Pale yellow, oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 30 tablets/PTP (for export)