Maxibufen Syrup (Dexibuprofen)

Child dose

For children aged 6 months and older, a dose of 0.4 to 0.6 mL/kg (5 to 7 mg/kg of dexibuprofen) should be taken every 4 to 6 hours as needed, not exceeding 4 times a day (28 mg/kg).

This medicine should be discussed with a doctor or pharmacist if the individual regularly consumes over 3 drinks of alcohol a day, as it may cause gastrointestinal bleeding. It may increase the risk of cardiovascular disease, thus individuals with heart disease or risk factors should be especially cautious. If cardiovascular symptoms arise, inform a healthcare professional immediately. Those with a history of gastrointestinal disease should use this medication with caution due to risks of gastrointestinal bleeding, ulcers, or perforation. Special care should be taken with the elderly, who are at an increased risk of gastrointestinal adverse reactions. Individuals with peptic ulcer, severe liver or kidney impairment, severe heart failure, hypertension, drug allergy, or a history of asthma should not use this medicine. Individuals with blood disorders or bleeding tendencies, impaired liver or kidney function, the elderly, or those with autoimmune diseases should use this medicine with caution. Rarely, this medicine can cause severe allergic reactions, skin rashes, liver dysfunction, kidney damage, or blood disorders, so if any unusual symptoms appear, discontinue use immediately and consult a doctor. Pregnant women, especially in late pregnancy, should avoid this medication as it may harm the fetus, and should only take it after consulting with a doctor during pregnancy. Breastfeeding women should stop nursing or discontinue this medication, as it can transfer into breast milk and cause adverse reactions in infants. Child and elderly dosages should be used at the minimum dosage with careful observation for any adverse reactions. Long-term use requires regular blood tests and liver and kidney function tests, and immediate discontinuation should occur if abnormalities are detected. Interactions may occur when used with other non-steroidal anti-inflammatory drugs, aspirin, diuretics, antihypertensives, anticoagulants, etc., so consult with healthcare professionals. Avoid excessive alcohol consumption during use, and seek medical attention immediately if symptoms of gastrointestinal bleeding or cardiovascular abnormalities appear. This medicine should be kept out of reach of children, and care should be taken as changing containers can lead to degradation of quality or accidents.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, shock, aplastic anemia, hemolytic anemia, granulocytopenia, thrombocytopenia, impaired platelet function, eosinophilia, peptic ulcer, gastrointestinal bleeding, perforation, ulcerative colitis, bloody stool, Stevens-Johnson syndrome, Lyell's syndrome, DRESS syndrome, acute generalized exanthematous pustulosis, jaundice (yellowing of skin or eyes), asthma attacks, severe rashes with high fever, blisters, skin peeling

Mild side effects

• Nausea
• indigestion
• itching
• vomiting
• abdominal pain
• nausea
• diarrhea
• gastric discomfort
• dry mouth
• stomatitis

Drug interactions

Do not use this medicine in combination with other non-steroidal anti-inflammatory drugs, aspirin, or high-dose methotrexate. Consult a doctor or pharmacist if using concurrently with glucocorticoids, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, diuretics, antihypertensives, ACE inhibitors, furosemide, lithium, low-dose methotrexate, or anticoagulants (such as warfarin).

Food interactions

Caution is advised when taking this medicine with alcohol.

This medication should be stored in a container that protects it from light, as it may be sensitive to light. It is important to store it at room temperature between 15 to 25 degrees Celsius to maintain its effectiveness.

Appearance

A light red to light orange syrup with a grape flavor, contained in a brown glass bottle or a white plastic bottle.

Package unit

Bottle - 50 milliliters/bottle, Bottle - 500 milliliters/bottle, Box - 1 bottle/box [75mL], Box - 1 bottle/box [100mL]