Rozaplus F Tablets

Adult dose

The usual adult dosage is 1 tablet containing 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide once daily. The maximum dose can be increased to 1 tablet containing 100 mg of losartan potassium and 25 mg of hydrochlorothiazide once daily. It can be taken regardless of meals, and the maximum blood pressure-lowering effect typically appears about 3 weeks after starting treatment. Specific dosing guidance: 1. For substitution therapy, each adjusted single therapy can be substituted with this medication.

Child dose

There is no experience with the use of this medication in children and adolescents (under 18 years old), so it should not be administered.

This medication can cause serious harm to the fetus during pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Patients with hypersensitivity to this medication, certain kidney and liver diseases, and some electrolyte imbalances should not take this medication. Patients with low blood pressure or kidney function issues, the elderly, and those with diabetes should use this medication cautiously, and it is important to regularly monitor blood pressure and kidney function during treatment. As this medication contains hydrochlorothiazide, electrolyte imbalances, particularly hypokalemia or hypercalcemia, may occur, so periodic blood tests to check electrolyte status are necessary. This medication can make the skin sensitive to ultraviolet light, so sun exposure should be avoided, and if skin abnormalities occur, a doctor should be consulted immediately. Various side effects such as cough, dizziness, rash, and gastrointestinal disturbances may occur, so if symptoms persist or worsen, consult a healthcare professional. Interactions may occur when used with other medications, so if you are taking other medications, you must inform your doctor or pharmacist. Dizziness or drowsiness may occur when driving or operating machinery, so caution is advised. This medication is not recommended for children or adolescents, and it should be stored in a safe place out of the reach of children.

Serious side effects

Hives, severe swelling (edema), angioedema (swelling of lips and eyelids and facial rash), angioedema (swelling of the larynx/pharynx that may cause airway obstruction, swelling of the face/lips/throat/tongue), chest tightness, difficulty breathing, respiratory distress, acute respiratory distress syndrome (ARDS), skin exfoliation, hemolysis, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), jaundice (intrahepatic cholestasis)

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, the storage temperature should be maintained between 1 and 30 degrees Celsius to preserve the medication's efficacy and safety.

Appearance

Pale yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle