Lozatine Plus F Tablet

Adult dose

Take 1 tablet of losartan potassium 50 mg / hydrochlorothiazide 12.5 mg once daily. The maximum dose is 1 tablet of losartan potassium 100 mg / hydrochlorothiazide 25 mg once daily. If blood pressure is not controlled after 3 weeks of treatment, an increase in dosage may be considered. Patients with renal impairment should receive the usual dose if creatinine clearance is 30 mL/min or more. It is recommended not to administer to patients with liver impairment.

Child dose

There is no experience with the use in children and adolescents, therefore the combination of losartan-hydrochlorothiazide is not administered to children and adolescents.

This medication can cause serious harm to the fetus if taken during pregnancy, especially during the second and third trimesters, and should be discontinued immediately upon confirmation of pregnancy. Use should be avoided in patients with certain allergic reactions or severely impaired kidney function, severely compromised liver function, and those with certain genetic metabolic disorders. Caution should be taken when administering this medication to patients with low blood pressure or dehydration, renal or liver issues, and electrolyte imbalances such as hyperkalemia or hypokalemia. As this medication lowers blood pressure, dizziness or drowsiness may occur at the beginning of treatment or when the dosage is increased. The hydrochlorothiazide component can cause electrolyte imbalances, so regular blood tests should be performed to monitor electrolyte levels. This medication may increase sensitivity to sunlight, so it is important to avoid prolonged exposure to ultraviolet light, and to consult a doctor immediately if any skin abnormalities occur. During treatment with this medicine, potassium supplements or potassium-containing salt substitutes should not be taken without consulting a physician. This medication may interact with other antihypertensive medications or specific drugs, so it is essential to inform healthcare providers of any other medications being taken. Safety and efficacy have not been established for use in children or adolescents. It is important to consult healthcare providers immediately if any abnormal symptoms or discomfort occur during treatment.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory issues with cough and fever, yellowing of the skin or eyes (jaundice), extreme malaise, sudden and severe headache, lightning headache, seizure, confusion of consciousness, visual disturbances, paralysis, urination.

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light and should be stored in a container that protects it from light. Additionally, it should be stored at room temperature, specifically between 1°C and 30°C, to maintain its efficacy and safety.

Appearance

Pale yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle