Lozatine Plus Tablet

Adult dose

Losartan Potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily, 1 tablet. If blood pressure is not adequately controlled, the dose may be increased, with a maximum dose of Losartan Potassium 100 mg/Hydrochlorothiazide 25 mg once daily, 1 tablet. This medication can be taken regardless of meals and is initiated when monotherapy is insufficient in effect.

Child dose

Due to lack of experience in pediatric and adolescent use, the losartan-hydrochlorothiazide combination is not administered to children and adolescents.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters; therefore, it should be discontinued immediately upon confirmation of pregnancy. This medication should not be administered to patients with certain diseases or conditions, such as those with severely impaired kidney function, severe liver impairment, or allergies, as it may pose risks. Patients with low blood pressure or electrolyte imbalances, those with gout or hyperuricemia, and the elderly require special caution when using this medication. While taking this medication, regular blood tests to monitor electrolytes and kidney function should be conducted, paying particular attention to ensure potassium levels do not become too high or too low. This medication may cause side effects such as dizziness, cough, skin rash, muscle pain, and dyspepsia, and in severe cases, serious reactions such as angioedema or cardiac arrhythmias may occur, so patients should consult a doctor immediately if any unusual symptoms arise. Additionally, this medication may interact with certain drugs, so it is essential to inform the doctor or pharmacist if other medications are being taken. Containing hydrochlorothiazide, this medication may increase skin sensitivity to sunlight, so it is recommended to avoid sun exposure and use sunscreen as needed. There is a possibility of dizziness or drowsiness while driving or operating machinery, so caution is advised, especially during the initial stages of treatment or when doses are changed. This medication is not to be used in children, and breastfeeding women should either discontinue breastfeeding or stop using this medication. Finally, this medication should be stored out of reach of children and kept sealed in its original container for safety.

Serious side effects

Hives, severe swelling (edema), angioedema (swelling of the lips and eyelids and facial rash), chest tightness, difficulty breathing, acute respiratory distress syndrome (ARDS), shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, jaundice (cholestatic jaundice), sudden and severe headache, seizures, confusion of consciousness, visual disturbances

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light, so it should be stored in an opaque container. Additionally, to safeguard the medication, it is best to store it at room temperature, that is, between 1 degree and 30 degrees Celsius.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle