Rozal Plus Tablet

Adult dose

The usual dose for adults is 50 mg of Losartan Potassium / 12.5 mg of Hydrochlorothiazide taken once daily in one tablet. A dose exceeding 100 mg of Losartan Potassium / 25 mg of Hydrochlorothiazide is not desirable. If blood pressure is not controlled, the dosage may be increased gradually. It can be administered regardless of meals, and the maximum blood pressure-lowering effect appears around three weeks after the start of treatment. In patients with kidney impairment, creatinine

Child dose

There is no experience using this medication in children and adolescents (under 18 years old), so this medication will not be administered.

This medication can cause serious harm or death to the fetus when taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be given to certain patients. For example, patients who are allergic to this medication or its components, have severely impaired kidney function, have severe liver dysfunction, or are pregnant should not take it. Additionally, patients with very low blood pressure, kidney problems, hypercalcemia, or gout should use this medication cautiously and consult their doctor before taking it. Regular checks of blood pressure, kidney function, and electrolyte levels should be performed during the use of this medication to monitor for abnormalities. This medication may increase potassium levels in the blood, so it can be dangerous to take it with potassium supplements or other medications that contain potassium without consulting a doctor. The hydrochlorothiazide component may cause electrolyte imbalances, so caution is advised especially if symptoms like vomiting or diarrhea occur; severe symptoms should be reported to medical personnel immediately. Some patients may experience side effects such as skin rash, headache, dizziness, or cough, and if a severe allergic reaction occurs, the medication should be stopped immediately and a healthcare professional consulted. During treatment, avoid excessive sun exposure, and report any unusual skin changes to a doctor immediately. This medication has insufficient experience for use in children and adolescents, so it should not be administered to them. In elderly patients, adverse reactions may occur more frequently, so they should take it with caution. Caution should be taken in case of dizziness or drowsiness while driving or operating machinery. It is advisable to avoid grapefruit juice during treatment, and if other medications are being taken, inform the doctor or pharmacist as there may be interactions with other drugs. This medication should be stored out of reach of children and kept in its original container with the lid tightly closed.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, mucosal pain in the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, breathing abnormalities associated with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning-like headache, seizures, confusion of consciousness, visual abnormalities, paralysis, urine

Mild side effects

• Abdominal pain
• swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infections
• weakness/fatigue
• diarrhea

This medication is sensitive to light and should be stored in a tightly sealed container that blocks light. The appropriate storage temperature is between 1°C and 30°C at room temperature.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle