Neurotan Plus Tablet

Adult dose

The usual dose for this medication is 1 tablet of Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily. A dosage exceeding 100 mg of Losartan Potassium / 25 mg of Hydrochlorothiazide per day is not recommended. If the effect of monotherapy is insufficient, start with Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily, and if after 3 weeks blood pressure is still uncontrolled, it can be increased to the maximum dose of Losartan Potassium.

Child dose

There is no experience regarding the use of this medication in children and adolescents, so it should not be administered.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. Patients with hypersensitivity to this medication, anuria, severe liver dysfunction, or severe renal impairment should not take it. Patients with hypotension, impaired renal function, liver disease, hyperuricemia, or gout should use this medication with caution. As this medication lowers blood pressure, dizziness or drowsiness may occur during the initial weeks of treatment, requiring caution when driving or operating machinery. During treatment, it is important to regularly check electrolyte levels in the blood, particularly potassium and sodium concentrations, for any abnormalities. This medication should not be taken with potassium-sparing diuretics or potassium supplements without medical advice, as it may dangerously elevate serum potassium levels. The hydrochlorothiazide component can cause sensitivity to sunlight, increasing the risk of skin rash or non-melanoma skin cancer; therefore, sun exposure should be limited and protective measures taken. If symptoms of dehydration or electrolyte imbalance occur during treatment, such as thirst, weakness, muscle cramps, nausea, or vomiting, immediate consultation with a healthcare professional is recommended. Pregnant or nursing women should avoid taking this medication, as it may cause adverse reactions in infants during breastfeeding. Elderly patients may experience more frequent side effects, requiring special caution during treatment. This medication may interact with other antihypertensive drugs, diuretics, certain analgesics, and antibiotics, so it is essential to inform your doctor or pharmacist about any other medications being taken.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, chest tightness, shortness of breath, severe rash accompanied by fever, blisters, skin peeling, pain in oral/ocular mucous membranes, jaundice of the skin or eyes, generalized weakness, sudden and severe headache, seizures, confusion, vision changes, paralysis, significantly reduced urine output, severe edema associated with elevated blood pressure, angioedema, vasculitis, anaphylaxis, pulmonary edema, acute kidney injury

Mild side effects

• Abdominal pain
• edema/swelling
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light and should be stored in a container that blocks light. Additionally, it is important to store it at room temperature, between 1 to 30 degrees Celsius, to maintain its effectiveness.

Appearance

Pale yellow oval film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle