Lopin Plus Tablet (Losartan Potassium, Hydrochlorothiazide)

Adult dose

The usual dose for adults is 1 tablet of Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily. Doses exceeding Losartan Potassium 100 mg / Hydrochlorothiazide 25 mg daily are not advisable. Patients with hypertension uncontrolled by either losartan or hydrochlorothiazide monotherapy should initiate treatment with Losartan Potassium 50 mg / Hydrochlorothiazide 12.5 mg once daily.

Child dose

Due to lack of experience with pediatric and adolescent populations, the losartan-hydrochlorothiazide combination should not be administered to children and adolescents.

This medication can cause serious harm to the fetus when taken during pregnancy, especially in the second and third trimesters. Discontinue use immediately if pregnancy is confirmed. Patients with hypersensitivity, certain electrolyte imbalances, or severe liver or kidney dysfunction should not take this medication. Patients with hypotension or kidney function problems, as well as those with a history of liver disease, should take this medication with caution and undergo regular blood tests and health checks during treatment. As this medication lowers blood pressure, symptoms such as dizziness, drowsiness, and orthostatic hypotension may occur, so caution is needed when driving or operating machinery. Do not take potassium supplements or potassium-containing salt substitutes without consulting a physician while on this medication; inform healthcare providers about any other medications to avoid potential interactions. Due to the hydrochlorothiazide component, the skin may become sensitive to sunlight, so avoid sun exposure, and consult a physician immediately if any skin abnormalities occur. Safety and efficacy of this medication in pediatric and adolescent populations have not been established, so it is not used in these groups. Elderly patients may experience more frequent adverse reactions while taking this medication, requiring careful monitoring by healthcare providers. If any adverse reactions occur during treatment, consult a physician immediately, especially for symptoms of hypotension, edema, rash, or respiratory distress, which require prompt action. Store this medication out of the reach of children, and keep it sealed in its original container.

Serious side effects

Hives, severe swelling (edema), angioedema (including swelling of the lips and eyelids and facial rashes), chest tightness, difficulty breathing, anaphylactic reaction, angioedema (leading to airway obstruction causing laryngeal/glottic swelling, facial/lip/pharyngeal/tongue swelling), severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, Stevens-Johnson syndrome,

Mild side effects

• Abdominal pain
• swelling/inflammation
• palpitations
• back pain
• dizziness
• cough
• sinusitis
• upper respiratory tract infection
• weakness/fatigue
• diarrhea

This medication is sensitive to light, so it should be stored in a container that does not allow light in. Maintain storage temperature between 1 and 30 degrees Celsius to preserve the effectiveness and safety of the medication.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle