Lopin Plus F Tablets (Losartan Potassium, Hydrochlorothiazide)

Adult dose

The usual dose for this medication is 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide taken once daily as one tablet. Dosages exceeding 100 mg of losartan potassium and 25 mg of hydrochlorothiazide per day are not advisable. For patients whose blood pressure is not controlled with either losartan or hydrochlorothiazide monotherapy: start with a regimen of 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide taken once daily as one tablet.

Child dose

There is no experience in using this medication in children and adolescents, so the combination of losartan and hydrochlorothiazide is not administered to children and adolescents.

This medication can cause serious harm to the fetus if taken during pregnancy, especially during the second and third trimesters. Therefore, if pregnancy is confirmed, discontinuation should occur immediately. Patients with allergies to any of the ingredients in this medication or certain kidney, liver, or electrolyte abnormalities should not take it. Patients with hypotension or impaired kidney function should use this medication with caution and follow a doctor's instructions. Electrolyte imbalances may occur due to the hydrochlorothiazide component, so it is important to check electrolyte levels regularly through blood tests. Dizziness or drowsiness may occur while taking this medication, so caution is advised when driving or operating machinery. Interactions with other medications may occur, so it is essential to inform your doctor or pharmacist of any other medications you are taking. Particularly, caution is necessary when taking potassium supplements or medications containing potassium, as this may lead to dangerously high potassium levels in the blood. The hydrochlorothiazide component may cause sensitivity to sunlight, increasing the risk of skin cancer; therefore, sun exposure should be avoided, and protective measures should be taken. Due to insufficient experience in children and adolescents, this medication is not recommended for use in that population. Elderly patients may experience side effects more frequently, so caution is advised when taking this medication. In the case of overdose, hypotension or heart-related side effects may occur; therefore, the prescribed dosage must be strictly adhered to, and medical advice should be sought in case of unusual symptoms. This medication should be stored in its original container and kept out of reach of children.

Serious side effects

Hives, severe swelling (including angioedema), chest tightness, difficulty breathing, cold sweats, pallor, potential airway obstruction due to angioedema, severe rash with fever, blisters, skin peeling, pain of the mucous membranes of the mouth/eyes, yellowing of the skin or eyes (jaundice), extreme fatigue throughout the body, acute hepatitis, sudden and severe headache, lightning-like headache, seizures, confusion, vision changes, paralysis, significant decrease in urine output.

Mild side effects

Abdominal pain, swelling, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory infection, weakness/fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, chest pain, facial swelling, fever, orthostatic hypotension, fainting, angina, arrhythmias (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular incident, hypotension, myocardial infarction, secondary atrioventricular block, appetite loss, constipation, toothache, dry mouth, dyspepsia, flatulence, gastritis,

This medication is sensitive to light and should be stored in a container that does not allow light in. Additionally, it should be stored at room temperature between 1 degree and 30 degrees Celsius, and extreme heat or cold should be avoided.

Appearance

Light yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle