Kozartan Plus Tablet

Adult dose

The usual dose for adults is one tablet of Losartan potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily. Doses exceeding Losartan potassium 100 mg/Hydrochlorothiazide 25 mg per day are not desirable. 1. If blood pressure is not controlled with monotherapy of Losartan or Hydrochlorothiazide, start with one tablet of Losartan potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily.

Child dose

There is no experience in using this medication in children and adolescents (under 18 years), so it should not be administered.

This medication can cause serious harm or death to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so it must be stopped immediately upon confirmation of pregnancy. This medication should not be used in patients with certain allergies, severely impaired kidney function, severe liver dysfunction, pregnant women, and patients with certain genetic lactose intolerance. Use this medication with caution in patients with specific conditions such as hypotension, kidney disease, liver dysfunction, systemic lupus erythematosus, hyperkalemia, or the elderly. As this medication lowers blood pressure, dizziness or drowsiness may occur initially or after a dose adjustment, so caution is needed. The hydrochlorothiazide component can cause electrolyte imbalances, requiring regular blood tests to check potassium, sodium, etc., and extra caution is needed during severe vomiting or diarrhea. This medication may interact with other drugs, so if you are currently taking any medications, inform your doctor or pharmacist. In particular, if taken with potassium supplements or medications containing potassium, blood potassium levels may increase to dangerous levels, so do not take it without consulting a doctor. If any new lesions or unusual changes appear on the skin while taking this medication, inform medical personnel immediately, minimize sun exposure, and take appropriate protective measures. If breastfeeding, consult a doctor regarding whether to continue breastfeeding or discontinue the medication, as this medication may be passed to the baby through breast milk. This medication is not used in children or adolescents due to insufficient safety and efficacy data. In case of overdose, symptoms such as low blood pressure, rapid heartbeat, and bradycardia may occur, so seek appropriate medical treatment immediately.

Serious side effects

• Hives, severe swelling (edema), angioedema (swelling of lips and eyelids, facial rash), angioedema (laryngeal/pharyngeal edema that may cause airway obstruction), chest tightness (may include chest pain), difficulty breathing (including dyspnea), cold sweats (not reported but may be associated with hypotension), pallor (not reported but may be associated with hypotension)
• Severe rash with high fever

Mild side effects

• General: Abdominal pain, weakness/fatigue, diarrhea, nausea, headache, lethargy, fever, orthostatic hypotension, fainting
• Cardiovascular: Palpitations, angina, arrhythmias, hypotension, myocardial infarction, secondary atrioventricular block
• Gastrointestinal: Loss of appetite, constipation, toothache, dry mouth, dyspepsia, flatulence, gastritis, vomiting, nausea, diarrhea, abdominal pain, intestinal vascular edema
• Musculoskeletal: Back pain, arm pain, joint pain, arthritis, fibromyalgia, hip pain, joint swelling, knee pain,

This medication may be sensitive to light, so it should be stored in a container that prevents light exposure. Additionally, it should be kept at a normal room temperature, between 1 and 30 degrees Celsius, away from excessively hot or cold places.

Appearance

Yellow oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle