Mezetrol Suspension (Megestrol Acetate)

Adult dose

(Tablets) 1. Breast cancer: Administer megestrol acetate orally at a total daily dose of 160 mg in 4 divided doses (40 mg, 1 tablet per dose, 4 times daily). 2. Endometrial cancer: Administer this medicine orally at a total daily dose of 40～320 mg in divided doses. The treatment period should be considered adequate to assess the effect of this medicine; continue administration for at least 2 months. (Suspension) Shake well and take megestrol acetate at a total daily dose of 800 mg (20 mL). In clinical trials, clinical effects were demonstrated with a daily dose of 400～800 mg (10∼20 mL) of this medicine.

This drug can pose serious risks to the fetus if used by pregnant women; therefore, it should not be taken by pregnant women or those who may become pregnant. Long-term use may lead to the onset of diabetes or worsen existing diabetes, and may cause hormonal irregularities known as Cushing's syndrome. If taken for a long time or suddenly stopped, adrenal function may weaken, and symptoms such as low blood pressure, nausea, or dizziness should be discussed with a physician. The artificial sweetener aspartame contained in this drug should not be administered to patients with a genetic disorder called phenylketonuria, and care should be taken not to exceed the recommended amount. Those allergic to this drug or its components should not use it. Patients with a history of thrombosis or vascular problems, as well as those with diabetes, should use this drug cautiously as it may affect blood sugar control. Various side effects such as diarrhea, rash, abdominal distension, high blood pressure, nausea, headache, and fever may occur during use, and if symptoms are severe, medical assistance should be sought. This drug is used to treat weight loss but should be used only after the cause is accurately identified, as long-term use may increase the risk of respiratory infections. Women who are breastfeeding should stop nursing as this drug can be passed to the baby through breast milk, posing risks. The safety and efficacy for children have not been established, so it is advisable not to use it in pediatric patients. There is no specific antidote for overdose, and dialysis is not effective, so adherence to the prescribed dosage is essential. This drug should be stored out of reach of children and should not be transferred to another container for safety. Animal studies indicate that this drug may affect reproductive function, so caution is needed if planning for pregnancy.

Diarrhea

This drug should be stored in a tightly sealed container that blocks light, and the storage temperature should be maintained between 15 and 25 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

A white to cream-colored suspension with an orange scent and flavor in an opaque container that disperses easily when shaken.

Package unit

14 packets (10 mL/packet x 14), 7 packets [20 mL/packet x 7]