Aricept (Donepezil Hydrochloride)

Adult dose

Administer 5 mg of Donepezil Hydrochloride once a day before bedtime. If experiencing unusual dreams, nightmares, or sleep disturbances, consideration may be given to morning administration. Normal levels are reached after 15 days, and a 5 mg dose is administered for 4 to 6 weeks. After evaluating clinical response, the dose may be increased to 10 mg, with caution regarding gastrointestinal adverse reactions. Underweight females over 85 years of age should take 5 mg per day.

Child dose

No experience in pediatric use.

This medication contains Donepezil Hydrochloride as the active ingredient and is used for the treatment of symptoms of Alzheimer's-type dementia. This medication should not be used in certain patients. For example, it should not be given to those who are allergic to this medication or its components, pregnant women or women who may become pregnant, breastfeeding women, and patients with lactose intolerance or certain genetic metabolic disorders. Patients with heart conditions or conduction disturbances may experience bradycardia or arrhythmias when using this medication, so caution is advised. Additionally, patients with a history of peptic ulcers or those taking non-steroidal anti-inflammatory drugs should use this medication cautiously as it may exacerbate gastrointestinal problems. Individuals with a history of asthma or obstructive pulmonary diseases may experience worsened symptoms due to bronchoconstriction or increased mucus secretion, so caution is warranted. Patients with extrapyramidal disorders, such as Parkinson's disease, may also experience worsened symptoms. This medication contains a dye called Yellow No. 5; individuals allergic to this component should exercise caution. Severe side effects can occur with this medication, so if symptoms such as fainting, heart issues, gastrointestinal bleeding, liver dysfunction, cerebrovascular disorders, muscle abnormalities, respiratory distress, acute pancreatitis, or acute renal failure appear, consult a doctor immediately. Various side effects, such as hallucinations, insomnia, dizziness, diarrhea, nausea, vomiting, fatigue, myalgia, rashes, itching, swelling, anxiety, excitation, aggressive behavior, drowsiness, depression, confusion, delusions, irritability, insomnia, talkativeness, mania, nightmares, psychiatric disturbances, delusions, urinary disorders, incontinence, frequent urination, high blood pressure, thrombocytopenia, anemia, leukopenia, thrombocytopenia, fever, temperature decrease, pain may also occur, so inform medical personnel of any unusual symptoms. This medication is not used for memory disorders other than dementia, and discontinuation should be considered if there is no therapeutic effect. Patients with heart disease or electrolyte abnormalities may require an ECG, and this medication may enhance the effects of muscle relaxants during anesthesia, so inform medical personnel before anesthesia. This medication is metabolized in the liver, so patients with reduced liver function should use it cautiously, and it may interact with other medications, so be sure to inform your healthcare provider of any other medications you are taking. It is recommended that pregnant or breastfeeding women do not use this medication unless absolutely necessary, in which case they should consult with a specialist before using it. Safety in pediatric patients has not been established, so it is not used in children. In cases of overdose, severe nausea, vomiting, bradycardia, respiratory depression, convulsions may occur, and immediate medical attention should be sought. This medication should be stored out of reach of children and should not be transferred to other containers for safety.

Serious side effects

Fainting, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcers, duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizure, cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (motor dysfunction, ataxia, dyskinesia, dystonia, tremors, involuntary movements, gait disorders, abnormal posture, speech disorders), neuroleptic malignant syndrome (akinesia, extreme rigidity, dysphagia, empty

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• dizziness
• insomnia
• drowsiness
• tremors

Store this medication in a tightly closed container to prevent air exposure and at a temperature between 1 and 30 degrees Celsius. Storing it this way will help maintain the medication's effectiveness and prevent degradation.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle