Peptazole Tablets 20 mg (Pantoprazole Sodium Sesquihydrate)

Adult dose

1. Treatment of mild reflux esophageal disease and associated symptoms Administer pantoprazole 20 mg orally once daily before breakfast. Symptom relief generally occurs within 2 ∼ 4 weeks, and healing can usually be achieved with 4 weeks of treatment. If healing has not occurred, it may be achieved with an additional 4 weeks of treatment. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis Administer pantoprazole 20 mg once daily before breakfast. If recurrence occurs, increase the dose to pantoprazole 40 mg daily, then reduce it again to 20 mg daily after healing. 3. Prevention of gastroduodenal ulcers caused by nonsteroidal anti-inflammatory drugs in patients who require continuous treatment with nonsteroidal anti-inflammatory drugs Administer pantoprazole 20mg once daily. No dose adjustment is necessary in elderly patients or patients with renal impairment. In patients with severe hepatic impairment, do not exceed pantoprazole 20 mg once daily.

This medication should not be administered to certain patients. Patients with hypersensitivity to this medication, its ingredients, or benzimidazole derivatives may experience severe allergic reactions when using this medication. Additionally, patients taking specific antiviral drugs such as Atazanavir, Nelfinavir, or Rilpivirine should avoid using this medication together, as interactions may reduce its efficacy. It is safer not to use this medication in women during the first three months of pregnancy or those who may become pregnant, and in nursing mothers. Patients with genetic metabolic disorders such as lactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take this medication due to the lactose it contains. Various side effects may occur when taking this medication. Gastrointestinal symptoms such as abdominal pain, constipation, abdominal bloating, diarrhea, nausea, vomiting, and dry mouth are commonly reported. Systemic symptoms like fatigue, weakness, lethargy, edema, fever, and elevated body temperature may also occur. Serious liver damage, manifested as liver dysfunction, jaundice, or liver failure, has been reported. Allergic reactions such as anaphylactic shock, urticaria, and angioedema may occur, necessitating immediate consultation with healthcare professionals if symptoms arise. Neurological and psychiatric symptoms like myalgia, arthralgia, headache, dizziness, visual disturbances, insomnia, depression, hallucinations, and confusion should also be noted. In severe cases, rhabdomyolysis, blood disorders, and severe skin diseases may develop. Long-term use of this medication necessitates regular monitoring. Particularly with usage exceeding one year, stomach acidity may decrease, hindering the absorption of vitamin B12, warranting caution. Elderly patients over 65 years or those with a history of gastric ulcers, duodenal ulcers, or gastrointestinal bleeding may have an increased risk of gastrointestinal bleeding with this medication and should use it with caution. Prolonged usage may also pose risks of hypomagnesemia, increased fracture risk, and the possibility of gastric polyps, hence the lowest effective dose and shortest duration of use are recommended. Dizziness or visual disturbances may occur while taking this medication, warranting caution when driving or operating machinery. There is potential for interactions with specific medications, so if other medications are being used, it is essential to inform the physician or pharmacist. Caution is especially needed when used with anticoagulants, antiviral drugs, and methotrexate. It is not safe for pregnant or nursing women to use this medication, and its experience in pediatric patients is limited, making it not recommended for children under 12 years of age. While no specific symptoms indicate an overdose, if symptoms appear, immediate consultation with a healthcare professional is advised for appropriate treatment. This medication should be taken whole, without chewing or crushing, and should only be used for the minimum dose and appropriate duration as directed by a physician during long-term use. Keep out of reach of children, and do not transfer to other containers. Lastly, some tumor occurrences related to this medication have been reported in animal studies, necessitating caution with long-term use.

Anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, urticaria, abdominal pain, constipation, distension, diarrhea, gastric polyp, nausea, vomiting, belching, dry mouth, fatigue, weakness, lethargy, edema, increased body temperature, fever, elevated liver enzyme levels, increased bilirubin, liver failure, arthralgia, myalgia, rhabdomyolysis, bone fracture, headache, dizziness, visual disturbances, taste abnormalities, insomnia, sleep disorders, depression, hallucinations, confusion, disorientation, interstitial nephritis, itching, skin erythema, angioedema, mucocutaneous syndrome, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, photosensitivity, hyperglycemia, agranulocytosis, leukopenia, thrombocytopenia, pancytopenia, gynecomastia, hyperlipidemia, lipid elevation, weight changes, hyponatremia, hypomagnesemia, elevated CK, anxiety, asthenia, back pain, bronchitis, chest pain, increased cough, dyspepsia, shortness of breath, flu-like symptoms, gastroenteritis, gastrointestinal disorders, tension, infection, migraine, cervical pain, pain, pharyngitis, rectal disorders, rhinitis, elevated AST, sinusitis, upper respiratory infection, frequent urination, urinary tract infection, carbuncle, allergic reaction, chills, furuncle, facial swelling, general edema, flushing, hernia, abnormal clinical laboratory tests, malaise, moniliasis, tumor, nonspecific drug reaction, ECG abnormalities, angina, arrhythmia, atrial fibrillation, coronary artery disease, congestive heart failure, hemorrhage, hypertension, hypotension, myocardial infarction, myocardial ischemia, palpitations, retinal vascular disease, syncope, tachycardia, phlebitis, thrombosis, vasodilation, decreased appetite, aphthous stomatitis, colitis, duodenitis, swallowing difficulties, enteritis, esophageal bleeding, esophagitis, gastric and duodenal tumor, gastric and duodenal bleeding, gastric and duodenal moniliasis, gingivitis, halitosis, hematemesis, increased appetite, melena, mouth ulcer, oral moniliasis, periodontal abscess, periodontitis, rectal bleeding, gastric ulcer, bowel movement abnormalities, tongue discoloration, ulcerative colitis, diabetes, goiter, gallbladder pain, hyperbilirubinemia, cholecystitis, cholelithiasis, jaundice, hepatitis, elevated ALP, anemia, petechiae, eosinophilia, iron deficiency anemia, leukocytosis, dehydration, gout, thirst, weight gain, weight loss, arthritis, bone disease, joint disease, leg cramps, bursitis, tendinitis, abnormal dream, confusion, convulsion, dry mouth, verbal dysphasia, hyperactivity, decreased libido, restlessness, neuralgia, neuritis, neuropathy, abnormal sensation, decreased reflex actions, abnormal perception, tremors, asthma, epistaxis, hiccups, laryngitis, respiratory distress, pneumonia, voice changes, acne, alopecia, contact dermatitis, eczema, fungal dermatitis, herpes simplex, herpes zoster, lichen planus dermatitis, papular rash, skin disease, skin ulcer, sweating, amblyopia, cataracts, hearing loss, diplopia, otalgia, paralysis, glaucoma, otitis externa, tinnitus, albuminuria, balanitis, mastalgia, cystitis, irregular menstruation, dysuria, epididymitis, hematuria, erectile dysfunction, nephrolithiasis, renal pain, nocturia, prostate disorders, pyelonephritis, scrotal edema, urethral pain, urethral disorders, urinary abnormalities, vaginitis, Clostridium difficile-associated diarrhea, hypocalcemia, hypokalemia, DRESS syndrome, microscopic colitis, systemic lupus erythematosus, skin lupus erythematosus

This medication should be stored in a tightly sealed container protected from light, maintaining a temperature between 1°C and 30°C at room temperature. Storing it this way will help maintain its efficacy for a longer period.

Appearance

Yellow, enteric-coated oval tablet

Package unit

28 tablets/bottle