Uride Tablets (Itopride Hydrochloride)

Adult dose

○ Adults: Administer itopride hydrochloride orally at a dose of 50 mg 3 times daily before meals. Reduce the dose appropriately according to symptoms.

This medication should not be used in patients with the following conditions: First, individuals who have an allergic reaction to this medication or any of its components, or have a history of hypersensitivity should not use it. Second, this medication should not be used in patients with gastrointestinal bleeding, mechanical obstruction, or perforation, where stimulating gastrointestinal motility may be harmful. Third, this medication contains lactose, so patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take it. Serious adverse reactions may occur during the use of this medication, so caution is needed. For example, severe allergic symptoms such as shock or anaphylaxis may occur, so if signs such as low blood pressure, respiratory distress, or hives appear, medication should be stopped immediately, and healthcare personnel should be informed. Liver dysfunction or symptoms of jaundice may also occur, thus liver function tests should be monitored along with the patient's condition. Moreover, gastrointestinal symptoms such as nausea, diarrhea, constipation, abdominal pain, and increased saliva, as well as neurological symptoms such as headaches, anxiety, sleep disturbances, and dizziness may occur. Endocrine and hematologic abnormalities such as gynecomastia, increased prolactin levels, decreased platelet count, and decreased white blood cell count have also been reported, necessitating caution. Renal dysfunction, elevated liver enzymes, rash, itching, tremors, chest pain, and fatigue may also occur rarely. This medication enhances the action of acetylcholine; therefore, if gastrointestinal symptoms do not improve, it is advisable to avoid prolonged use. Co-administration with anticholinergics may reduce the efficacy of this medication, so care should be taken to adjust the interval of administration. Pregnant women or women who may become pregnant should only use this medication when the benefits of treatment outweigh the risks, as safety has not been established. During breastfeeding, this medication may be excreted in breast milk, so it is recommended to avoid administration if possible; if unavoidable, it is advisable to discontinue breastfeeding. Finally, this medication should be used cautiously in children, as safety has not been sufficiently confirmed, and elderly patients should be monitored closely as they may be more susceptible to adverse reactions due to decreased bodily function. Lastly, this medication should be stored out of reach of children, and transferring it to another container should be avoided due to the risk of accidents and quality deterioration.

• Shock
• symptoms resembling anaphylaxis
• hypotension
• respiratory distress
• laryngeal edema
• urticaria
• pallor
• diaphoresis
• liver dysfunction
• jaundice

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it is best to keep the medication at room temperature, specifically between 1°C and 30°C, avoiding excessively hot or cold locations. Proper storage will help maintain the medication’s effectiveness.

Appearance

White round film-coated tablets

Package unit

500 tablets/bottle, 30 tablets/bottle