Inhifla Tablet (Clopidogrel Sulfate)

Adult dose

For patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, administer 75 mg of clopidogrel once daily orally. For patients with acute coronary syndrome (unstable angina or non-ST elevation myocardial infarction), administer a loading dose of 300 mg orally once on the first day, followed by 75 mg once daily for maintenance. At this time, aspirin 75 - 325 mg should be administered once daily in conjunction with this medication.

This medication prevents blood from clotting by inhibiting platelet aggregation. The effectiveness of this medication may be reduced in individuals with genetic variations leading to low function of a specific enzyme (CYP2C19); alternative treatments should be considered in such cases. Concomitant use with drugs that activate certain enzymes may increase medication concentrations and raise the risk of bleeding, hence should be avoided. Patients with a known allergy to this medication or those with bleeding, severely impaired liver function, nursing women, or individuals with certain genetic conditions should not take this medication. Patients at high risk of bleeding or those scheduled for surgery must exercise caution when taking this medication, and if bleeding symptoms occur, they should consult a physician immediately. The risk of bleeding may increase if taken with other medications that also increase bleeding risk. During treatment with this medication, bleeding may take longer to stop; notify healthcare professionals if bleeding is severe or prolonged. This medication can rarely cause thrombocytopenia or serious blood disorders; visit a hospital immediately if fever or signs of infection occur. Possible side effects include gastrointestinal disturbances, headache, dizziness, rash, etc., though these are usually mild. During pregnancy, the risk to the fetus is not significant; however, due to the potential for bleeding during delivery, discontinuation before childbirth is recommended. During breastfeeding, this medication may be excreted in breast milk, and it's advisable to discuss whether to continue or discontinue breastfeeding with a physician. Elderly patients or those with impaired kidney function may have a higher risk of bleeding and should use caution. Overdose may increase bleeding risk, and as there is no specific antidote, treatment such as platelet transfusion may be necessary in case of severe bleeding. The safety and efficacy of this medication in children have not been established. During the course of this medication, inform your physician about the current use of this medication before starting new therapies or surgeries. This medication should be kept out of reach of children, and care should be taken not to transfer it to other containers as this may affect its quality.

Serious side effects

Intracranial hemorrhage, hemorrhagic stroke, severe bleeding (gastrointestinal bleeding, intracranial hemorrhage, ocular hemorrhage, hematuria, hemoptysis, etc.), fatal bleeding, thrombocytopenia, agranulocytosis, aplastic anemia, acquired hemophilia, severe allergic reactions (urticaria, angioedema, chest tightness, difficulty breathing, sweating, pallor), severe skin reactions (severe rash, blistering, skin peeling, pain in mucous membranes of mouth/eyes), dyspnea, asthma

Mild side effects

• Headache
• dizziness
• abdominal pain
• dyspepsia
• diarrhea
• nausea
• fatigue
• rash
• pruritus
• purpura

Store this medication in a tightly sealed container to protect it from air and moisture. It is best to keep it at room temperature, between 1 to 30 degrees Celsius.

Appearance

Pink round film-coated tablets

Package unit

30 tablets (10 tablets/Alu-Alu X 3), 30 tablets/bottle