Medication info

Dextenol Injection (Dexpanthenol)

Prescription medicationInjections정맥
Ingredient · strength
Dexpanthenol›250mg / 1mL
Manufacturer / importer
대한약품공업(주)
Appearance
A brown glass ampoule injection filled with a colorless-to-light yellow liquid
Packaging
2mL per ampoule × 50 pieces
Approval status
Active

MFDS item code 200604196 · Notified 2006.05.12 · Insurance code 645101181

Summary

Main use
Prevention and treatment of pantothenic acid deficiency, improvement of side effects and dermatitis
Who receives it
Adults
Adult administration
As Dexpanthenol, administer 20-100mg by intramuscular or intravenous injection once a day for 1-2 times. For postoperative intestinal paralysis, administer 50-500mg once a day for 1-3 times, which may be increased up to 6 times if necessary. Adjust according to age and symptoms. For intravenous injection, mix 500mg of this medication with intravenous fluids such as dextrose injection or lactated Ringer's solution for slow intravenous infusion.

Ingredients

Manufacturer
대한약품공업(주)

Efficacy & effects

Prevention and treatment of pantothenic acid deficiency, improvement of side effects and dermatitis

  • Pantothenic acid deficiency
  • wasting disease
  • hyperthyroidism
  • pregnant women
  • nursing mothers
  • side effects related to streptomycin and kanamycin
  • contact dermatitis
  • acute and chronic eczema
  • postoperative intestinal paralysis
View approved original text

This medication is used to prevent and treat pantothenic acid deficiency. Additionally, it is helpful in situations where the need for pantothenic acid increases or is not adequately obtained from the diet, such as in wasting diseases, hyperthyroidism, and during pregnancy and lactation. It is also used for the prevention and treatment of side effects of streptomycin and kanamycin, contact dermatitis, acute and chronic eczema, and various conditions suspected to be caused by pantothenic acid deficiency or metabolic disorders. Therefore, this medication is effective in improving and treating various pantothenic acid-related deficiency states and skin diseases.

How it is given

Adult administration

As Dexpanthenol, administer 20-100mg by intramuscular or intravenous injection once a day for 1-2 times. For postoperative intestinal paralysis, administer 50-500mg once a day for 1-3 times, which may be increased up to 6 times if necessary. Adjust according to age and symptoms. For intravenous injection, mix 500mg of this medication with intravenous fluids such as dextrose injection or lactated Ringer's solution for slow intravenous infusion.

Precautions

This medication is an ampoule injection, and caution must be taken when opening the container as glass fragments may enter. Special care is necessary when used by children or the elderly. This medication should not be used in patients with hemophilia. If symptoms of hypertension appear, use of this medication should be discontinued; therefore, cautious administration is required in patients with hypertension. Allergic reactions such as itching, rash, and hives may occur on the skin, and gastrointestinal symptoms such as vomiting or abdominal pain may rarely occur. Caution is necessary, as respiratory distress may occur if this medication is used within 5 minutes after administering a drug called suxamethonium. Blood pressure may drop slightly, and agitation may occur in the elderly. This medication should not be administered intravenously alone and should be used after a certain time interval following the administration of a parasympathomimetic or suxamethonium. Allergic reactions may rarely occur when used with antibiotics, anesthetics, or barbiturates, hence caution is necessary. In women, this medication may prolong the effect of suxamethonium. Pregnant or nursing women should only use this medication when the benefits outweigh the risks. Safety in children has not been established; therefore, it should be used cautiously. Additionally, it may be ineffective in patients with hypokalemia or mechanical bowel obstruction.

Side effects and when to seek care immediately

Serious side effects

Hives, respiratory distress

Mild side effects

  • Itching
  • pain in the injection site
  • red spots on the skin
  • generalized dermatitis
  • vomiting
  • abdominal pain
  • diarrhea
  • slight drop in blood pressure
  • mild agitation

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a closed container that blocks light and kept at room temperature between 1 and 30 degrees Celsius. Proper storage can maintain the medication's efficacy for a longer period.

Appearance and packaging

Appearance

A brown glass ampoule injection filled with a colorless-to-light yellow liquid

Package unit

2mL per ampoule × 50 pieces

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.