Losar 50 mg (Losartan Potassium)

Adult dose

The recommended dosage for adults is 50 mg orally once daily at the same time, regardless of meals. The maximum blood pressure-lowering effect usually appears 3 to 6 weeks after treatment initiation. If the therapeutic effect is inadequate, the dose can be split into two doses per day or increased to a maximum of 100 mg once daily. For patients with type 2 diabetes and hypertension, 50 mg once daily is usually prescribed, adjusted according to blood pressure.

Child dose

For children and adolescents aged over 6 years weighing between 20 kg and less than 50 kg, the recommended dosage is 25 mg once daily, which can be increased to a maximum of 50 mg once daily based on blood pressure response. Weight

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should not be taken by women who are pregnant or may become pregnant. Patients with hypersensitivity to this drug, severe liver dysfunction, hereditary angioedema, primary hyperaldosteronism, etc., should not take this medication. Elderly patients, those with hyperkalemia, liver dysfunction, valvular heart disease, and renal impairment should use this drug cautiously, paying particular attention to prevent excessive blood pressure reduction. During treatment, blood pressure, kidney function, and electrolyte levels should be regularly monitored to ensure there are no abnormalities, and it is advisable to avoid concomitant use of potassium supplements or potassium-containing medications as hyperkalemia may occur. This drug can impact liver function; if symptoms of hepatitis appear, the physician should be consulted immediately, as serious hepatitis or renal failure can occur, requiring caution. Rapid drops in blood pressure may cause dizziness and shock symptoms; if these occur, the medication should be stopped immediately and medical advice obtained. Dizziness or drowsiness may occur during driving or operating machinery while taking this drug, so caution is required. This medication should not be used in children, especially those under 6 years of age, as its safety and efficacy have not been adequately established. Overdose may lead to hypotension and tachycardia, and appropriate emergency treatment may be necessary. It is not recommended for breastfeeding women, and if it must be taken, breastfeeding should cease. It is advisable to avoid grapefruit juice during treatment, and due to potential interactions with some medications, consultation with a physician or pharmacist is necessary if other medications are being taken.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, angioedema, vasculitis, anaphylactic syndrome, severe rash with high fever, blisters, skin peeling, pain in mouth/eyes, dyspnea or difficulty breathing, asthma attacks, respiratory anomalies with coughing and fever, jaundice (yellowing of skin or eyes), severe general malaise, liver dysfunction, sudden and severe headache.

Mild side effects

• Nausea
• diarrhea
• dyspepsia
• cough
• sinusitis
• pharyngitis
• myalgia
• insomnia
• headache
• weakness/fatigue

This medication should be stored in a sealed container to prevent air or moisture from entering and should be kept at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the drug's effectiveness.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle