Celebrex Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient and may be administered without regard to meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis : Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS) : Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea : The recommended initial dose is 400 mg of celecoxib; if needed, an additional 200 mg may be administered on the first day of treatment. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment : For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be taken with caution by individuals who regularly consume more than three drinks a day, as it may cause gastrointestinal bleeding; it is essential to consult a doctor or pharmacist. It may increase the risk of cardiovascular issues, leading to severe problems such as myocardial infarction or stroke; hence, it should be used at the lowest effective dose and for the shortest duration possible, with careful monitoring for cardiovascular symptoms. Gastrointestinal perforations, ulcers, or bleeding may occur, especially in elderly people or those with a history of gastrointestinal issues, necessitating special caution. Individuals with hypersensitivity or a history of allergies, severe liver or kidney disease, active peptic ulcers, heart failure, and pregnant women should not take this medication. Those with compromised liver or kidney function, asthma, hypertension, heart failure, or diabetes should consult a doctor before use for careful administration. While taking this medication, various side effects such as dyspepsia, diarrhea, headaches, dizziness, hypertension, skin rashes, and edema may occur; any unusual symptoms should be reported to healthcare providers immediately. This medication is primarily metabolized in the liver; thus, its blood levels may vary if given with certain other medications, necessitating dosage adjustments. Women who are pregnant or planning to become pregnant should not take this drug, and nursing mothers should either avoid it or discontinue breastfeeding. Applicability and efficacy in children or adolescents under 18 years have not been established, making its use not advisable in this group. Elderly patients may have decreased kidney, liver, and heart function, requiring special precautions during use, along with regular blood tests and liver/kidney function evaluations. Dizziness or drowsiness may occur during treatment, necessitating caution while driving or operating machinery. Overdosage can lead to symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding, warranting immediate medical attention.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, hemorrhage, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, liver enzyme elevation, itching, rash, urticaria, angioedema, alopecia, blistering dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, decreased sensation, migraine, neuralgia, neuropathy, sensory disturbances, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, exacerbation of allergy, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic reaction, angioedema, anorexia, increased appetite, depression, nervous hyperreactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbated bronchospasm, dyspnea, laryngitis, pneumonia, nosebleeds, voice disorders, vesicular dermatitis, dermatitis, nail disorders, photosensitivity reactions, pruritus, erythematous rash, maculopapular rash, skin disorders, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, mucosal syndrome, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, drug rash, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, liver necrosis, cholestasis, cholestatic hepatitis, jaundice, acute renal failure, hyponatremia, menstrual disorders, chest pain, sacroiliitis, contact dermatitis, injection site reactions, skin nodules, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, ocular pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal impairment, interstitial nephritis, headache, dizziness, constipation, thirst, ulcerative stomatitis, gastritis, allergy, lumbago, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, RA factor positive, herpes zoster, pneumonia, dyspnea, elevated ALT, hearing loss

Store this medication in a tightly closed container to prevent moisture exposure, and it is best kept at room temperature between 15 to 30 degrees Celsius. This will help maintain the medication's effectiveness over time.

Appearance

A white capsule filled with a white to off-white powder with a blue stripe on both ends

Package unit

30 capsules (10 capsules/blister x 3), 100 capsules/bottle