Medication info
Kozaril Tablets (Losartan Potassium)

Kozaril Tablets (Losartan Potassium)

Prescription medicationTablet경구
Ingredient · strength
Losartan Potassium›50mg / 1 tablet
Manufacturer / importer
(주)넥스팜코리아
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 200600718 · Notified 2006.04.28 · Insurance code 662501590

Summary

Main use
Treatment of hypertension and kidney disease (in patients with type 2 diabetes)
Who takes it
Adults · Children
Adult dose
This medication can be taken regardless of meals, but it is advised to take it at the same time every day. For hypertension treatment, it is recommended to administer 50 mg of losartan potassium orally once daily, and if the therapeutic effect is insufficient, it may be divided into two doses or increased up to 100 mg once daily. For treatment of kidney disease in hypertensive patients with type 2 diabetes, the usual dosage is 50 mg once daily based on blood pressure.
Child dose
For children and adolescents aged 6 years and older weighing between 20 kg and 50 kg, the recommended dosage is 25 mg once daily, which may be increased up to 50 mg. For those weighing over 50 kg, it is 50 mg once daily.

Ingredients

Manufacturer
(주)넥스팜코리아

Efficacy & effects

Treatment of hypertension and kidney disease (in patients with type 2 diabetes)

  • Hypertension
  • kidney disease in patients with type 2 diabetes
View approved original text

This medication effectively lowers blood pressure in patients with hypertension, reducing the burden on the cardiovascular system. It also helps prevent and slow the progression of kidney disease in patients with hypertension and type 2 diabetes. Therefore, it is used in the treatment of hypertension and the resulting complication of kidney disease.

How to take

Adult dose

This medication can be taken regardless of meals, but it is advised to take it at the same time every day. For hypertension treatment, it is recommended to administer 50 mg of losartan potassium orally once daily, and if the therapeutic effect is insufficient, it may be divided into two doses or increased up to 100 mg once daily. For treatment of kidney disease in hypertensive patients with type 2 diabetes, the usual dosage is 50 mg once daily based on blood pressure.

Child dose

For children and adolescents aged 6 years and older weighing between 20 kg and 50 kg, the recommended dosage is 25 mg once daily, which may be increased up to 50 mg. For those weighing over 50 kg, it is 50 mg once daily.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately if pregnancy occurs. This medication should not be administered to certain patients, such as those with severely impaired liver function or hereditary angioedema. Elderly patients or those with impaired kidney function, or patients with hyperkalemia, should use this medication with greater caution and require regular blood tests and monitoring of their condition. During treatment, symptoms such as dizziness or blood pressure lowering may occur, so caution should be exercised when driving or operating machinery. This medication may interact with other drugs, especially potassium supplements or potassium-sparing diuretics, so they should not be taken together. Various side effects such as skin rash, angioedema, liver function abnormalities, muscle pain, dry cough, etc., may occur, and if any abnormal symptoms arise, one should consult a doctor immediately. Serious symptoms such as severe hypotension, renal failure, or allergic reactions may occur, so regular monitoring of blood pressure and kidney function is important. Overdosing on this medication may lead to symptoms such as hypotension and bradycardia, so the prescribed dosage must be strictly followed. Children, especially those under the age of 6 or with severely impaired kidney function, should not be given this medication. When storing, keep it out of the reach of children and do not transfer it to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and extreme headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

  • Muscle cramps
  • back pain
  • leg pain
  • dizziness
  • nasal congestion
  • upper respiratory infection
  • sinusitis
  • nausea
  • diarrhea
  • indigestion
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  • cough
  • sinus disorder
  • pharyngitis
  • muscle pain
  • insomnia
  • headache
  • weakness
  • fatigue
  • edema
  • bloating
  • abdominal pain
  • chest pain
  • swelling of lips
  • eyelids
  • facial rash
  • peeling of palms
  • hemolysis
  • facial swelling
  • fever
  • orthostatic effects
  • fainting
  • angina
  • second-degree AV block
  • hypotension
  • myocardial infarction
  • atrial fibrillation
  • palpitations
  • tachycardia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.