Sarpin 4 mg (Lacidipine)

Adult dose

1. Adults The therapeutic dose of this medicine should be appropriately adjusted according to the patient's response and the severity of symptoms. The initial dose is 2 mg of lacidipine once daily. It should be taken at the same time each day, preferably in the morning, regardless of meals. If a dose increase is needed, increase to 4 mg once daily after an appropriate period has elapsed to allow the pharmacological effect to be adequately assessed. Increase to 6 mg once daily only if blood pressure is not controlled with 4 mg once daily. The interval before increasing the dose should generally be at least 3 ～ 4 weeks, the time required for this medicine to achieve its full pharmacological effect, except in patients who require more rapid dose escalation. If an adequate response is not achieved, another antihypertensive agent may be added (a beta-blocker and/or a diuretic). 2. Patients with hepatic impairment Because this medicine is metabolized mainly in the liver, its bioavailability and blood pressure-lowering effect may be increased in patients with hepatic impairment. These patients should be monitored carefully, and a reduced initial dose is recommended. 3. Patients with renal impairment This medicine is not excreted through the kidneys; therefore, dose adjustment is not necessary in patients with renal impairment. 4. Elderly patients The initial dose is 2 mg once daily. If necessary, it may be increased to 4 mg once daily after 4 weeks.

Child dose

There is no experience using this medication in children.

This medication should not be used in certain patients. For example, individuals who are allergic to this drug or similar medications, pregnant or breastfeeding women, and patients with severe heart problems should not take it. Additionally, caution is advised for patients with liver dysfunction or issues with heart rhythm control, as well as those with unstable angina. While taking this medication, mild side effects such as dizziness, headache, palpitations, flushing, nausea, and skin rash may occur temporarily. Particularly, patients with heart disease need to be cautious as angina symptoms may worsen. Abrupt discontinuation of this medication may worsen symptoms; therefore, it must be reduced gradually as per a doctor’s instructions. Care must be taken when combining this medication with other antihypertensive drugs as it may cause blood pressure to drop too low. It is advisable not to take this with grapefruit juice, as it may alter the effects of the drug. Pregnant or breastfeeding women should not take this medication, and safety in children has not been established. In case of overdose, hypotension and abnormal heart rhythms may appear, and immediate medical assistance should be sought. This medication should be kept out of the reach of children and should not be transferred to another container for safety.

• Dizziness
• headache
• mood disorders
• tremors
• depression
• palpitations
• tachycardia
• flushing
• worsening of pre-existing angina
• syncope

This medication should be stored in a tightly sealed container to protect it from air and light, and it should be kept in a cool place below 30 degrees Celsius for safe use.

Appearance

White oval film-coated tablet

Package unit

30 tablets (10 tablets/PTP×3), 90 tablets (10 tablets/PTP×9)