Ozatam Plus Tablet 50/12.5, 100/25 milligrams

Adult dose

The usual adult dose is 1 tablet of losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once daily. The maximum dose is 1 tablet of losartan potassium 100 mg/hydrochlorothiazide 25 mg once daily. If blood pressure is not controlled, the dose may be increased after 3 weeks of treatment. - Start with 1 tablet of losartan potassium 50 mg/hydrochlorothiazide 12.5 mg once daily. - If needed, increase to losartan potassium 100 mg.

Child dose

There is no experience of use in pediatric and adolescent patients (under 18 years old), so it should not be administered.

This medication can cause serious harm to the fetus if used during pregnancy, especially during the second and third trimesters, so it must be discontinued immediately upon confirmation of pregnancy. Patients with allergies to this medication or its components, severe kidney or liver disease, and certain electrolyte imbalances should not take this medication. Particular caution is required when using this medication in patients with low blood pressure or impaired kidney function, liver disease, hyperuricemia or gout, and elderly patients. This medication may affect serum electrolyte levels, so regular blood tests to monitor potassium, sodium, and other levels are necessary. Due to the hydrochlorothiazide component, the skin may become sensitive to sunlight, so sun exposure should be avoided and skin protection should be considered during treatment. Dizziness or drowsiness may occur while taking this medication, so caution is needed when driving or operating machinery. This medication may interact with other drugs, so consultation with a physician is required, especially when taking potassium supplements, antihypertensives, diuretics, non-steroidal anti-inflammatory drugs, etc. Women who are pregnant or planning to become pregnant should consult their physician, and nursing mothers should also consult a healthcare professional before taking this medication. It is not recommended to use this medication in children and adolescents as safety and efficacy have not been established. If any unusual symptoms occur during treatment, immediately inform a physician and seek advice.

Serious side effects

Hives, severe swelling (edema), angioedema, vasculitis, hemolytic phenomena, cerebrovascular accident, angina, arrhythmia, myocardial infarction, secondary heart block, acute myopia, acute angle-closure glaucoma, jaundice, hepatitis, intrahepatic cholestatic jaundice, aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia, necrotizing vasculitis, pneumonia and pulmonary edema, acute respiratory distress syndrome (ARDS), acute renal failure, cerebrovascular disorder, severe allergy.

Mild side effects

• General: Abdominal pain
• weakness/fatigue
• diarrhea
• nausea
• headache
• bronchitis
• pharyngitis
• malaise
• fever
• orthostatic hypotension

This medication is sensitive to light, so it should be stored in a tightly sealed container that blocks light. Also, it is important to maintain a temperature between 1 to 30 degrees Celsius when storing the medication. Storing it this way preserves the drug's effectiveness and safety.

Appearance

Yellow oval film-coated tablet

Package unit

50/12.5mg: 30 tablets/bottle, 300 tablets/bottle 100/25mg: 30 tablets/bottle