Losarzen Tablets (Losartan Potassium)

Adult dose

This medication can be taken with or without food, but it is recommended to take it at the same time every day. For treating hypertension, the initial and maintenance dose is recommended to be 50 mg orally once daily as Losartan Potassium. The maximum blood pressure-lowering effect appears 3 to 6 weeks after treatment initiation. If the treatment effect is insufficient, the same dose can be split into two doses daily, or increased to a maximum of 100 mg once daily as needed.

Child dose

For children and adolescents over 6 years of age: (1) For patients weighing 20 kg or above but less than 50 kg, a dose of 25 mg once daily is administered, with a maximum of 50 mg once daily depending on the patient's blood pressure response.

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the 2nd and 3rd trimesters, thus it should not be used by women who are pregnant or may become pregnant. If pregnancy is confirmed, this medication should be discontinued immediately, and regular examinations are necessary to monitor the health status of the fetus. This medication should not be administered to patients with severe liver or kidney impairment, certain genetic diseases, or those with a history of allergic reactions. Elderly patients, those with significantly low blood pressure, high serum potassium levels, or those with heart or vascular diseases should take this medication with caution. Blood pressure and kidney function should be regularly monitored during treatment as there may be risks of excessively low blood pressure or kidney function issues. Drug interactions may occur if combined with other medications, so consultation with a doctor or pharmacist is advised, especially regarding the concurrent use of potassium supplements or potassium-containing medications, which can be dangerous. Rare side effects such as skin rashes, headaches, dizziness, muscle pain, and digestive disorders may occur, and if severe allergic reactions or angioedema happen, intake must be stopped immediately and medical attention sought. If a pregnant woman takes this medication, severe side effects such as low blood pressure or reduced kidney function may occur in the newborn, so close monitoring of the infant's condition is necessary. This medication is not recommended for breastfeeding women, and it is advisable to stop breastfeeding while on this medication. Children, particularly those under 6 years of age or with severe kidney impairment, should not take this medication. In cases of overdose, low blood pressure and heart rhythm abnormalities may occur, so immediate medical attention should be sought if suspected. Dizziness or drowsiness may occur during driving or operating machinery while taking this medication, so caution is needed.

Serious side effects

Hives, severe swelling (edema), angioedema (laryngeal/glottic swelling causing airway obstruction, swelling of the face/lips/pharynx/tongue), chest tightness, difficulty breathing, anaphylaxis-like syndrome (discomfort, oral numbness, sweating, hives, difficulty breathing, systemic flushing, edema), severe rash with high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough and fever.

Mild side effects

• Muscle cramps
• back pain
• leg pain
• dizziness
• nasal congestion
• upper respiratory infection
• sinusitis
• nausea
• diarrhea
• dyspepsia

This medication should be stored in a tightly sealed container to protect it from air and moisture. The storage temperature should ideally be maintained between 1 degree and 30 degrees Celsius at room temperature to preserve its effectiveness.

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle