Unifenac E.F. Injection (Diclofenac β-Dimethylaminoethanol)

Adult administration

Inject 90mg of diclofenac beta-dimethylaminoethanol deep into one side of the upper buttock each day. In severe cases, 90mg may be administered twice a day, alternating sides for each injection. After the initial treatment, the administration can be switched to tablets or suppositories. Adjust accordingly based on age, disease, and symptoms. To minimize cardiovascular adverse reactions, the lowest effective dose should be used for the shortest duration.

This medication should be discussed with a doctor or pharmacist before use by individuals who regularly consume more than three glasses of alcohol daily. Caution is required as this medication can cause gastrointestinal bleeding. Individuals with cardiovascular diseases or risk factors are at higher risk of severe cardiovascular problems such as myocardial infarction or stroke when taking this medication. Therefore, if such symptoms appear, immediate consultation with medical personnel is necessary. This medication can cause severe issues such as gastrointestinal bleeding, ulcers, or perforation, so particular caution is needed when used by elderly patients or those with a history of gastrointestinal diseases. Severe allergic reactions can manifest symptoms similar to myocardial infarction, so if chest pain occurs, the medication should be stopped immediately and medical personnel should be notified. When using ampoule injections, care should be taken to avoid glass fragments during cutting the container, especially when administering to children or the elderly. Patients with peptic ulcers, severe blood disorders, liver dysfunction, renal impairment, hypertension, cardiac failure, or known allergies to this medication's ingredients should not take it. Patients with a history of asthma or aspirin allergies may experience severe allergic reactions to this medication, so its use should be avoided. Patients with a history of peptic ulcers, those with weak liver or kidney function, hypertensive patients, patients with cardiac failure, asthma patients, children, and the elderly should use this medication cautiously. This medication can rarely cause shock, gastrointestinal bleeding, blood disorders, severe skin reactions, liver dysfunction, renal impairment, allergic reactions, and neurological symptoms. If any unusual symptoms occur during use, the medication should be stopped immediately and a consultation with a medical professional is required. This medication should be used at the lowest effective dose for the shortest possible duration, and regular blood tests along with liver and kidney function tests may be needed for long-term use. Particularly hypertensive patients should frequently check their blood pressure while taking this medication, and caution is required as fluid retention or edema may occur. There may be interactions if taken with other non-steroidal anti-inflammatory drugs, antihypertensives, diuretics, anticoagulants, etc., so it is necessary to inform medical personnel about their use. Use of this medication during pregnancy, especially in late pregnancy, should be avoided, and it should be used cautiously in early pregnancy. If breastfeeding, this medication can pass into breast milk and affect the baby, so breastfeeding should be stopped or medication should be discontinued. Elderly and pediatric patients should be particularly cautious of adverse reactions while taking this medication.

Serious side effects

Hives, swelling, chest tightness, difficulty breathing, rash, skin peeling, pain in oral/ocular mucosa, jaundice, acute renal failure, oliguria, hematuria, severe allergic reactions, Stevens-Johnson syndrome, Lyell syndrome, severe skin adverse reactions, asthma attacks, cardiovascular thrombotic reactions, myocardial infarction, stroke, cardiac failure, Kounis syndrome, severe gastrointestinal bleeding, peptic ulcer, blood disorders (granulocytopenia, thrombocytopenia

Mild side effects

• Loss of appetite
• nausea
• vomiting
• abdominal pain
• diarrhea
• stomatitis
• thirst
• constipation
• headache
• drowsiness

This medication should be stored in a closed container that blocks light and kept at room temperature between 1°C and 30°C. Storing it this way helps maintain the effectiveness of the medication and prevents degradation.

Appearance

A transparent solution that is colorless to yellowish in a brown ampoule injection.

Package unit

2mL × 50 ampoules