Pendilazine (Phenmetrazine tartrate)

Adult dose

As Phenmetrazine tartrate, administer 35 mg orally 2 to 3 times a day, one hour before meals. The dose should use the minimum effective amount and be adjusted individually. For some patients, a single daily dose of 17.5 mg may be appropriate. The dose should not exceed 70 mg per time or 3 times per day. It is to be used for a short duration (within 4 weeks), and if satisfactory weight loss is achieved within the first 4 weeks, treatment can continue.

This medication should only be used alone for a short duration, as using it in conjunction with other appetite suppressants may lead to serious heart problems. Long-term use of this medication significantly increases the risk of a severe lung condition known as pulmonary hypertension, so immediate cessation should occur if symptoms arise, and a medical evaluation is necessary. There is a risk related to heart valve disease, and the heart condition should be thoroughly checked before using this medication; it is better not to take it if there are heart murmurs or valve issues. Patients with specific diseases or conditions, such as hypertension, hyperthyroidism, glaucoma, cardiovascular diseases, mental anxiety states, or a history of drug abuse, should not take this medication. Children under 16 years of age or women who are pregnant or may become pregnant should also avoid this medication. This drug affects the central nervous system and may cause side effects such as anxiety, insomnia, dizziness, so caution is needed when operating machinery or driving. Diabetic patients may need to adjust their insulin dosage when taking this medication, so they should consult with healthcare professionals. Severe overdose symptoms and cardiovascular abnormalities can occur with excessive intake, so it should be prescribed at the minimum effective dose, as sudden discontinuation may lead to extreme fatigue and depression. Women who are pregnant or nursing should refrain from taking this medication, as its safety has not been established. This medication falls under narcotic substances and has the potential for abuse, thus it must be strictly used according to a doctor's instructions, and abrupt discontinuation after long-term high-dose use may result in mental issues. It should be stored in a safe place out of reach of children.

Serious side effects

Hives, swelling of the lower extremities (may indicate pulmonary hypertension)

Mild side effects

• Palpitations
• tachycardia
• increased blood pressure
• overstimulation
• anxiety
• dizziness
• insomnia
• tremors
• euphoria
• headache

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is preferable to maintain storage temperatures between 1 degree and 30 degrees Celsius to safely preserve the medication's effectiveness.

Appearance

White, round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle