Nabugen Tablet (Nabumetone)

Adult dose

This medicine is for oral use. Swallow it without chewing (tablets only). ○ Adults: Administer 1 g of nabumetone orally once daily at bedtime. If symptoms are severe or persistent, or worsen rapidly, an additional 500 mg∼1 g of this medicine may be administered orally in the morning. ○ Older adults: As with many other medicines, blood concentrations may be higher in older patients. Do not exceed a maximum daily dose of 1 g; in some cases, a dose of 500 mg may provide satisfactory symptom relief.

Child dose

○ Children: Clinical data on the use of this preparation in children are not yet available.

This medication may pose a risk of gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages a day; therefore, it is necessary to consult a doctor or pharmacist. This medication can affect the cardiovascular system and may increase the risk of serious cardiovascular diseases such as myocardial infarction or stroke. Patients with a history of cardiovascular disease or risk factors should be particularly cautious. This medication can cause severe gastrointestinal side effects such as gastrointestinal bleeding, ulcers, and perforation, which may be more dangerous for the elderly or patients with a history of gastrointestinal diseases. Thus, such patients should start with the minimum dose and discontinue use immediately if symptoms of gastrointestinal bleeding appear. Patients with peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, cardiac dysfunction, or those with hypersensitivity to this medication or a history of aspirin-induced asthma should not take this medication. Patients with blood disorders, liver dysfunction, kidney dysfunction, cardiac dysfunction, chronic airway diseases, allergic rhinitis, hypertension, heart failure, autoimmune diseases, as well as the elderly must use this medication carefully and require regular checks and monitoring. This medication can rarely cause various adverse reactions, including shock, anaphylaxis, skin rashes, liver dysfunction, kidney dysfunction, gastrointestinal bleeding, neurological issues, and respiratory problems; thus, if any unusual symptoms arise, it is important to inform medical personnel immediately. This medication should be administered at the lowest possible dose and for the shortest duration. If taken long-term, regular blood tests and liver and kidney function tests are necessary. This medication should not be used in conjunction with other non-steroidal anti-inflammatory drugs, and it may interact with certain blood pressure medications, diuretics, anticoagulants, and anticonvulsants, so any other medications being taken should be disclosed. Pregnant women or women who could become pregnant, nursing mothers, and children under 15 years old should not take this medication. Elderly patients are at a higher risk for gastrointestinal bleeding and perforation, so the minimum dose should be administered, and symptoms of gastrointestinal bleeding should be closely monitored for the first four weeks. In case of overdose, symptoms such as headache, nausea, gastrointestinal bleeding, coma, and convulsions may appear; since there is no specific antidote, it is crucial to visit a medical facility immediately for appropriate treatment. This medication should be kept out of reach of children and should not be transferred to another container.

• Shock
• anaphylactic-like symptoms
• dyspnea
• urticaria
• hypotension
• angioedema
• facial edema
• rash
• itching
• dyspepsia

This medication should be stored in a tightly closed container to prevent air or moisture from entering and should ideally be kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle