Zenadip Tablet (Lercanidipine Hydrochloride)

Adult dose

As Lercanidipine Hydrochloride, take 5 to 10 mg orally once daily at least 15 minutes before meals. The dose can be increased up to 20 mg depending on patient symptoms. Dose adjustments should be made gradually, as the maximum antihypertensive effect becomes evident within 2 weeks. Caution is advised for elderly patients and those with liver or kidney impairments, and it should not be given to patients with severe liver or kidney impairment.

This medicine should not be used in certain patients. For example, it should not be taken by women who are pregnant or breastfeeding, those allergic to this medicine or similar drugs, patients with heart problems, severe liver or kidney diseases, and children or adolescents under 18 years old. Moreover, patients with heart rhythm device abnormalities or mild to moderate liver or kidney diseases, those with a history of angina, frequent alcohol consumers, and the elderly should exercise increased caution when using this medicine. Taking this medicine may cause symptoms such as flushing of the face or swelling of the hands and feet, and in rare cases, it can lead to low blood pressure or chest pain. Other potential side effects include headache, dizziness, indigestion, nausea, vomiting, and fatigue. It may affect liver function, so liver function tests should be conducted regularly, and if abnormalities are detected, the medication should be discontinued. Additionally, consult a physician if symptoms such as oral inflammation, skin rash, or muscle pain occur. This medicine should not be abruptly discontinued as it may worsen symptoms; dosage should be tapered off gradually. Exercise caution when driving or operating machinery if experiencing dizziness or drowsiness. Since this medication is metabolized in the liver, its effects may vary when taken with certain drugs. It should not be taken with specific antifungals, antibiotics, immunosuppressants, anticonvulsants, or grapefruit juice, and alcohol consumption should be avoided. Women who are pregnant or may become pregnant, as well as breastfeeding women, are advised not to take this medication, and it should not be used in those under 18 years of age due to lack of experience. Elderly patients require special attention, and overdose can lead to serious hypotension or heart issues, requiring immediate medical attention. Finally, this medicine should be kept out of reach of children, and transferring it to another container may alter its quality, so caution is warranted.

Serious side effects

Severe swelling (including peripheral edema), chest pain, angina, cold sweat, difficulty breathing.

Mild side effects

• Flushing
• peripheral edema
• palpitations
• tachycardia
• headache
• dizziness
• weakness
• fatigue
• drowsiness
• neurosis

This medicine should be stored in a tightly sealed container to prevent exposure to air or moisture. It is recommended to keep it at room temperature between 1 to 30 degrees Celsius.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle