Harmobic Capsule (Meloxicam)

Adult dose

1. Acute exacerbations of osteoarthritis (degenerative arthritis): ○ Adults: Administer meloxicam 7.5 mg orally once daily. If symptoms do not improve, the dose may be increased to 15 mg per day as needed. 2. Rheumatoid arthritis, ankylosing spondylitis: ○ Adults: Administer meloxicam 15 mg orally once daily. The dose may be reduced to 7.5 mg per day according to response to treatment. Do not administer more than 15 mg of this product per day. Take the daily dose all at once, with water or another beverage during a meal. ○ In elderly patients or patients at increased risk of adverse reactions (e.g., history of gastrointestinal disease or cardiovascular risk factors), treatment is usually started at a dose of 7.5 mg per day. ○ Do not administer more than 7.5 mg per day to patients with severe renal impairment undergoing hemodialysis.

This medication may cause gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages a day, so it is essential to consult a doctor or pharmacist. This medication can increase the risk of cardiovascular diseases, so individuals with a history of heart disease or stroke, or with risk factors, should carefully monitor cardiovascular symptoms during treatment. Serious gastrointestinal side effects such as gastrointestinal bleeding, ulcers, or perforation may occur, so those with a history of gastrointestinal diseases or the elderly should take caution. This medication may cause severe allergic reactions or dermatitis, so if symptoms such as skin rash or mucous membrane damage occur, discontinue use immediately. It may affect kidney function, so if you have kidney diseases or are taking diuretics or antihypertensive medications, kidney function should be monitored regularly. Women who are pregnant or planning to become pregnant should not take this medication, and nursing mothers should also avoid it. Before taking this medication, inform your doctor about any pre-existing conditions such as allergic reactions, liver disease, kidney disease, cardiovascular diseases, and all medications you are currently taking. Dizziness, drowsiness, and blurred vision may occur during use, so caution should be exercised when driving or operating machinery. It is advisable to take this medication at the minimum effective dose for the shortest duration possible, and regular blood tests, as well as liver and kidney function tests, are necessary with long-term use. Concomitant use with other non-steroidal anti-inflammatory drugs, aspirin, anticoagulants, etc., can increase the risk of bleeding, so concomitant administration should be avoided or closely monitored. Overdose may result in gastrointestinal bleeding, renal failure, liver failure, heart problems, etc., so adhere to the prescribed dosage and seek immediate medical attention if overdose occurs. Keep out of reach of children, and store the medication in its original container and sealed.

Gastrointestinal bleeding, serious cardiovascular thromboembolic reactions, myocardial infarction, stroke, bleeding from the stomach or intestines, ulcers, perforation, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, anaphylactic reactions, interstitial nephritis, glomerulonephritis, renal medullary necrosis, nephrotic syndrome, elevated serum transaminases, elevated liver function tests, increased plasma creatinine, increased blood urea nitrogen, aplastic anemia, bone marrow suppression, changes in blood counts, leukopenia, thrombocytopenia, anemia, decreased plasma iron, reduced hemoglobin, decreased hematocrit, increased neutrophils, increased eosinophils, increased basophils, increased monocytes, agranulocytosis, anaphylaxis, malaise, confusion, loss of orientation, mood changes, mood disorders, insomnia, nightmares, anxiety, increased appetite, depression, hypersensitivity, dizziness, drowsiness, headache, cranial discomfort, fatigue, lethargy, taste dysfunction, mental clouding, convulsions, sensory disturbances, tremors, blurred vision, conjunctivitis, foreign body sensation in the eye, conjunctival hemorrhage, tinnitus, palpitations, increased blood pressure, flushing, arrhythmia, tachycardia, hypotension, hypertension, myocardial infarction, angina pectoris, heart failure, vasculitis, cough, upper respiratory tract infections, asthma, bronchospasm, dyspnea, dyspepsia, nausea, vomiting, abdominal pain, constipation, bloating, diarrhea, loss of appetite, peptic ulcers, occult or visible gastrointestinal bleeding, stomatitis, gastritis, esophagitis, belching, dry mouth, angular cheilitis, occult blood in stool, gastrointestinal perforation, colitis, pancreatitis, melena, perforated peptic ulcer, hepatitis, angioedema, vesicular dermatitis, erythema multiforme, photosensitivity reactions, contact dermatitis, fixed drug eruption, urinary retention, elevated plasma creatinine levels, increased urea levels, decreased total protein, decreased albumin, proteinuria, glycosuria, increased urine sediment, hematuria, sodium and fluid retention, hyperkalemia, acute renal failure, decreased urine output, frequent urination, urinary tract infections, interstitial nephritis, edema, lower limb edema, malaise, fever, facial edema, syncope, weight loss, weight gain, axillary and breast pain, arthralgia, low back pain, axillary and chest pain, stiffness, lower limb weakness, female infertility, delayed ovulation, dehydration, drowsiness, nausea, vomiting, epigastric pain, hypertension, acute renal failure, liver failure, respiratory depression, coma, convulsions, cardiovascular collapse, cardiac arrest

This medication is sensitive to light, so it should be stored in a container that protects it from light. Additionally, it is advised to store the medication at room temperature between 1°C and 30°C. This will help maintain the drug's efficacy safely.

Appearance

Hard capsules in upper and lower dark green containing a yellowish powder

Package unit

30 capsules/bottle, 100 capsules/bottle