Couparin Tablet 5 mg (Warfarin Sodium)

Adult dose

Individual requirements vary according to PT/INR and specific genotypes of the CYP2C9 and VKORC1 genes (see 4. General Precautions under Precautions for Use). The usual initial dose is 2～5 mg of warfarin sodium per day, and the maintenance dose is 2～10 mg per day. Lower doses are recommended for elderly or debilitated patients.

This medication prevents blood from coagulating and thrombus formation. However, it should not be used by patients at high risk for bleeding or those with bleeding disorders. Patients with severely impaired liver or kidney function and those with severe hypertension may also be at risk when taking this medication. Women who are pregnant or may become pregnant should not take it, as it can harm the fetus. The dosage of this medication may vary based on differences in specific genes, so regular blood coagulation tests are necessary. If bleeding symptoms occur, discontinue the medication immediately and consult a healthcare professional. There are many drug interactions, and depending on the medicines taken concurrently, the effect of this medication may be enhanced or weakened, so all current medications should be disclosed to healthcare providers. Additionally, foods rich in vitamin K or alcohol may influence the effect of this medication, so caution is required. It is advisable to avoid activities that may result in trauma during exercise or activities. Side effects may include bleeding, skin necrosis, and liver dysfunction, so any abnormal symptoms should be reported immediately. Elderly patients or children may respond differently to this medication and require special caution. In case of overdose, severe bleeding may occur, requiring vitamin K administration or emergency treatment. Therefore, it is crucial to adjust the dosage under regular check-ups and as directed by healthcare providers while taking this medication.

Hemorrhage, gastrointestinal hemorrhage, urethral hemorrhage, submucosal hemorrhage, intramural hemorrhage, paralytic ileus, visceral dysfunction, excessive uterine bleeding, hemorrhagic necrosis, adrenal hemorrhage, paralysis, sensory disturbances, headache, chest pain, abdominal pain, joint pain, muscle pain, dizziness, shortness of breath, dyspnea, dysphagia, swelling, weakness, hypotension, shock, leukopenia, hypersensitivity reaction, pain, edema, asthenia, fever, fatigue, drowsiness, lethargy, cold intolerance, nausea, diarrhea, vomiting, abdominal pain, abdominal distension, elevated liver enzymes, hepatitis, jaundice, cholestatic liver injury, skin necrosis, calciphylaxis, alopecia, rash, pruritus, urticaria, dermatitis, cholesterol microembolism, purple toe syndrome, vasculitis, dysgeusia, anticoagulant-related nephropathy, calcification of the trachea or bronchial tubes, priapism

This medication is sensitive to light, so it should be stored in a dark place, and the temperature should be kept between 1 degree and 30 degrees Celsius at room temperature. This storage method helps to maintain the medication's efficacy and safety.

Appearance

Pale pink round tablet

Package unit

100 tablets/bottle