Dextibufen 400 mg (Dextibufen D.C.)

Adult dose

(Tablets) * 400 mg ○ Adults: Administer 400 mg of dexibuprofen orally 2～3 times daily. Do not exceed 1,200 mg of dexibuprofen per day.

This medication may pose a risk of gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages a day; therefore, consultation with a physician or pharmacist is required. Moreover, this medication may increase the risk of cardiovascular diseases, so patients with a history of heart disease or stroke, or those with risk factors must consult carefully before taking this medication. This medication can cause serious gastrointestinal issues such as bleeding, ulcers, or perforation; thus, elderly patients or those with a history of gastrointestinal diseases should be particularly cautious, and if abnormal symptoms appear, immediate consultation with medical personnel is required. People with gastrointestinal ulcers or bleeding, severe liver or kidney impairment, severe heart failure, severe hypertension, or a history of asthma should not take this medication. Taking this medication alongside aspirin or other nonsteroidal anti-inflammatory drugs may increase the risk of serious side effects, so co-administration is not advised. Furthermore, interactions may occur when taken with high doses of methotrexate or certain medications, so always consult with healthcare providers. This medication can be excreted in breast milk, potentially causing adverse reactions in infants; therefore, breastfeeding should be avoided or breastfeeding should be suspended while on this medication. During treatment, dizziness or fatigue may occur, requiring caution when driving or operating machinery. Pregnant women, especially after six months of pregnancy, may be at risk for the fetus; thus, women who are pregnant or planning to become pregnant must consult before taking this medication. Regular blood tests and liver and kidney function tests should be performed during treatment to check for abnormalities, and if any unusual symptoms occur, the medication should be stopped immediately, and medical personnel consulted. If severe allergic reactions, skin rashes, breathing difficulties, jaundice, blood abnormalities, or gastrointestinal bleeding symptoms occur, stop taking this medication immediately and seek medical attention. This medication should be used for the shortest duration with the minimum effective dose, and prolonged use requires close supervision by healthcare personnel. Children, elderly patients, and those with chronic diseases should be particularly cautious during treatment and should always carefully monitor for adverse reactions. In case of overdose, immediate medical attention should be sought, and emergency procedures such as gastric lavage or dilution may be required. This medication should be stored out of reach of children, away from direct sunlight, in a cool and dry place. Transferring to other containers may cause quality deterioration or accidents, so caution is advised.

Gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, bleeding of the stomach or intestine, ulcers, perforation, dyspepsia, abdominal distension, heartburn, upper abdominal pain, diarrhea, constipation, loss of appetite, nausea, vomiting, abdominal pain, gastric discomfort, esophagitis, esophageal stricture, diverticulitis exacerbation, nonspecific hemorrhagic colitis, ulcerative colitis, Crohn's disease, peptic ulcer, gastrointestinal bleeding, perforation, hematochezia, gastritis, pancreatitis, thirst, stomatitis, erythema multiforme, systemic lupus erythematosus, hair loss, angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis, eosinophilia, drug rash, acute generalized exanthematous pustulosis, rash, urticaria, itching, purpura, asthma attacks, eczema, anaphylactic reactions, photosensitivity reactions, jaundice, elevated ALT, elevated AST, elevated ALP, abnormal liver function, hepatitis, rhinitis, bronchospasm, acute pneumonia, neglect, malignancy, hearing loss, tinnitus, taste disturbance, fatigue, drowsiness, headache, dizziness, anxiety, restlessness, confusion, depression, aseptic meningitis, psychosis, agitation, excitement, sense of direction disturbance, reversible toxic neuropathy, hypotension, hypertension, palpitations, acute renal failure, oliguria, hematuria, proteinuria, elevated BUN, elevated serum creatinine, hyperkalemia, decreased urine output, generalized edema, shortness of breath, lethargy, renal papillary necrosis, nephrotic syndrome, interstitial nephritis, peripheral edema, acute pulmonary edema, fluid retention, Conn's syndrome, reduced female fertility, periorbital edema, malaise, fever, nosebleeds, exacerbation of inflammation, restlessness, facial edema, dyspepsia, pruritus, anaphylactic shock, rash, diarrhea, vomiting

This medication may be sensitive to air or moisture, so it should be stored in airtight containers. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature. This helps prolong the effectiveness of the medication.

Appearance

Pink, oblong film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle