Cardilex Extended Release Tablet 4mg (Doxazosin Mesylate)

Adult dose

1. Hypertension Most patients receive 4 milligrams once daily. It may take up to 4 weeks to achieve the optimal effect of this medicine. After 4 weeks of treatment, the dose may be increased to up to 8 milligrams once daily, depending on the patient's response. The maximum recommended daily dose is 8 milligrams. This medicine may be used as monotherapy for blood pressure control. If blood pressure is not adequately controlled with monotherapy, this medicine may be used in combination with a diuretic, beta-blocker, calcium antagonist, or ACE inhibitor. 2. Urinary retention and voiding disorders due to benign prostatic hyperplasia Most patients receive 4 milligrams once daily. The dose may be increased to up to 8 milligrams once daily, depending on the patient's response. The maximum recommended daily dose is 8 milligrams. It may be used in patients with prostatic hyperplasia regardless of whether they have hypertension. In patients with both hypertension and benign prostatic hyperplasia, both conditions may be treated simultaneously with monotherapy. As with other medicines of this type, monitoring of the patient is recommended at the start of treatment. There are no studies demonstrating whether increasing the dose to 8 milligrams increases efficacy. May be administered with or without food. Swallow whole with plenty of water. Older adults : The usual dose is recommended. Patients with renal impairment : The pharmacokinetics of doxazosin are unchanged in patients with insufficient renal function, and there is no evidence that doxazosin worsens renal failure. Therefore, the usual dose may be administered to these patients. There are no specific restrictions on the duration of use.

This medicine must be swallowed whole and should never be chewed, cut, or crushed. This medication should not be used in patients with hypersensitivity, hypotension, those with blockage in the intestine or esophagus, patients with narrowed gastrointestinal tract, or those with urethral problems due to benign prostatic hyperplasia, and patients with overactive bladder or poor kidney function. It should be administered with caution in patients with significant cardiac or liver problems, and special care is required in acute heart disease conditions. While taking this medication, various side effects including dizziness, headache, hypotension, fatigue, indigestion, skin itching, urination problems may occur, so any abnormal symptoms should be reported to a doctor. In particular, dizziness or fainting due to orthostatic hypotension may occur at the beginning of treatment; therefore, caution is necessary and the ways to prevent and handle such symptoms should be well understood during medication. When taken with other antihypertensives or PDE-5 inhibitors, the risk of hypotension may be increased, so it is necessary to inform the physician and take caution. Patients with poor liver function should be particularly careful when using this medication, and in cases of severe liver impairment, it is preferable not to use it. While taking this medication, if there are gastrointestinal motility disorders, the effectiveness of the drug may be reduced, so caution is necessary. Patients planning cataract surgery should inform their ophthalmologist about taking this medication since relaxation of the iris may occur during surgery as a side effect. Some of this medication may be excreted unchanged in the stool, so it is not a cause for concern if it appears in the stool. Women who are pregnant or breastfeeding should consult a doctor before taking this medication as its safety has not been established. The safety in children has not been sufficiently confirmed, so caution is required for use. Elderly patients may experience side effects like hypotension more frequently, so extra caution should be taken when using this medication. At the initial stages of taking this medication, care should be taken while driving or operating machinery due to the risk of accidents from dizziness and similar side effects. In case of overdose, the patient should be laid down and the head lowered to prevent hypotension, and suitable emergency treatment should be received if necessary. This medication should be kept out of reach of children, and transferring to another container may cause deterioration of quality or accidents, so caution should be observed.

Hypertension, dry mouth, fatigue, lumbar pain, chest pain, peripheral edema, orthostatic hypotension, dizziness, headache, confusion, abdominal pain, nausea, palpitations, tachycardia, myalgia, bronchitis, cough, pruritus, cystitis, urinary incontinence, influenza-like syndrome, dyspepsia, drowsiness, dyspnea, respiratory tract infection, rhinitis, urinary tract infection, penile priapism, allergic reaction, fatigue, facial flushing, lethargy, pain, weight gain, syncope, sensory impairment, paresthesia, tremor, gynecomastia, constipation, diarrhea, abdominal bloating, vomiting, leukopenia, purpura, thrombocytopenia, abnormal liver function tests, cholestasis, hepatitis, jaundice, arthralgia, muscle cramps, muscle weakness, anxiety, anorexia, depression, erectile dysfunction, irritability, exacerbation of bronchospasm, epistaxis, alopecia, skin rash, urticaria, blurred vision, tinnitus, intraoperative pupillary dilation syndrome, dysuria, hematuria, urination disorder, frequent urination, nocturia, polyuria, bradycardia, angina, myocardial infarction, cerebrovascular accident, deep vein thrombosis, gout

This medication should be stored in a tightly sealed container to prevent air exposure, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius. By storing it this way, the effectiveness of the medicine can be maintained, preventing deterioration.

Appearance

White film-coated tablet with a convex both sides and round shape

Package unit

30 tablets/bottle