Hyper Sustained Release 5 mg (Felodipine)

Adult dose

Swallow this medicine whole with water. Do not divide, chew, or crush it. Hypertension The initial dose is 5㎎ orally once daily, and the maintenance dose is 5-10㎎ daily, taken in the morning. Do not exceed the maximum daily dose of 20㎎. This medicine may be administered concomitantly with a β-blocker or diuretic, and may be administered as monotherapy when other antihypertensive agents are unsuitable. Adjust the dose according to the patient's response to treatment. Stable angina The initial dose is 5㎎ once daily and may be increased to 10㎎ as needed. This medicine may be administered concomitantly when a β-blocker does not provide an adequate effect. Adjust the dose according to the patient's response to treatment. Older adults Administer with caution while monitoring the patient's condition; consider an initial dose of 2.5㎎ once daily. Patients with renal impairment Renal impairment does not affect the plasma concentration of felodipine. Dose adjustment is not necessary, but administer with caution to patients with severe renal impairment (GFR<30ml/min). Patients with hepatic impairment The plasma concentration of felodipine may increase in patients with hepatic impairment, and they may respond to treatment at lower doses. Therefore, administer with caution to patients with hepatic impairment, considering an initial dose of 2.5mg once daily, and do not administer to patients with severe hepatic impairment.

Child dose

Safety and efficacy in children have not been established.

This drug should not be used in women who are pregnant or may become pregnant. It is also not safe to administer to patients with cardiogenic shock, where cardiac function has rapidly declined, or patients with heart valve issues. This medication is not recommended for patients with severely impaired liver function or those with poor cardiac function, acute myocardial infarction or unstable angina. Additionally, patients with genetic issues related to lactose should not take this medication. Caution is advised when using this medication in the elderly, heart failure patients, hypotensive patients, or patients with impaired liver or kidney function, as dosage adjustments may be necessary. When starting this medication or increasing the dosage, symptoms such as flushing, headache, palpitations, dizziness, and fatigue may occur. These symptoms are usually temporary and vary with dosage. Occasionally, symptoms such as ankle swelling, chest tightness, nausea, constipation, appetite loss, skin rash, and itching may arise, so if any abnormal symptoms occur, consult a healthcare professional. Discontinuing this medication abruptly can worsen symptoms; therefore, do not stop taking it without a doctor's instruction and gradually reduce the dosage. Caution is advised in activities that may be risky, such as high-altitude work or driving, as blood pressure can drop too low and cause dizziness. It is recommended to take this medication in the morning on an empty stomach or after a light meal. As this drug is metabolized in the liver, caution is needed if taken with certain medications, as blood concentration levels may change. In particular, concomitant use with certain antibiotics, antifungals, anticonvulsants, and grapefruit juice can increase or decrease the effects or side effects of this drug, so inform the healthcare professional of any medications being taken. It is advisable for women who are pregnant or breastfeeding to avoid this medication, and if necessary, to stop breastfeeding. Safety for pediatric patients has not been established, and there is insufficient experience, so it is generally not recommended. Elderly patients should start at a low dose and take it carefully while observing their condition. In case of overdose, there may be significant drops in blood pressure, cardiac rhythm abnormalities, or consciousness disturbances, so immediate medical attention is required. Finally, during the use of this medication, dizziness or fatigue may occur, so caution should be exercised when driving or operating machinery.

Facial flushing, headache, palpitations, dizziness, fatigue, tachycardia, feelings of suffocation, chest pressure, ankle swelling, hypotension accompanied by tachycardia that causes angina, extrasystole, heaviness in the head, vertigo, unsteadiness, lethargy, drowsiness, anxiety, sensory abnormalities, syncope, nausea, constipation, discomfort in the stomach, heartburn, abdominal pain, loss of appetite, diarrhea, thirst, vomiting, gingival hypertrophy, gingivitis, elevated AST, elevated ALT, elevated ALP, elevated LDH, elevated BUN, increased creatinine, anemia, rash, itching, exfoliative dermatitis, skin hyperemia, hives, photosensitivity reactions, vascular edema, leukocytoclastic vasculitis, myalgia, arthralgia, hyperglycemia, weight gain, peripheral edema, leg cramps, shoulder stiffness, weakness, finger tremor, cough, throat irritation, sweating, tearing, conjunctival injection, paresthesia, elevated CPK, increased total cholesterol, increased triglycerides, decreased serum potassium, gynecomastia, erectile dysfunction, sexual dysfunction, increased urinary frequency, angioedema, fever, confusion, sleep disorders, hypothermia, nausea, vomiting, bradycardia, atrioventricular block, atrioventricular dissociation, ventricular extrasystole, impaired contractility, impaired consciousness, coma, seizures, dyspnea, pulmonary edema, apnea, adult respiratory distress syndrome, acidosis, hypocalcemia

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is also advisable to store the medication at room temperature between 1°C and 30°C.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle