Nyrance Plus Tablets

Adult dose

For those aged 12 and older: Take 2 tablets once daily, or 1 tablet twice daily.

This medicine should not be taken by individuals who are allergic to this medicine or any ingredients contained in it. Moreover, infants under 12 months should not take this medicine. While taking this medicine, it is important not to take phosphates, calcium salts, oral tetracycline preparations, antacids, and drugs like levodopa together. Infants under 1 year old or individuals undergoing treatment from a physician, patients with oxalate nephropathy, pregnant women or women with the potential to become pregnant, nursing mothers, premature infants, and children should consult with a doctor or pharmacist before taking this medicine. Patients with gastrointestinal diseases such as peptic ulcers or chronic ulcerative colitis, individuals with heart or circulatory issues, kidney disorders, hypoalbuminemia, gout, or those with kidney stones should also consult with a specialist before taking this medicine. This medicine contains the dye yellow No. 5, so those allergic to or sensitive to this ingredient should take caution. If any adverse reactions such as upper abdominal discomfort, diarrhea, constipation, rash, nausea, vomiting, dermatitis, foul odor during sweating or breathing, hair loss, irritability, gastrointestinal disturbance, upper abdominal pain, hypotension, pulmonary edema, etc., occur while taking this medicine, discontinue use immediately and consult with health personnel. Additionally, if menstruation becomes more frequent or if the amount of bleeding increases significantly and lasts longer than usual, one should consult with a specialist immediately. Those taking oral contraceptives containing estrogen or with a predisposition to thrombosis need to be cautious, as taking vitamin E may increase the risk of thrombosis. Long-term high-dose use can lead to tolerance to the medicine. Long-term intake of pyridoxine up to 500 mg to 2 g per day may result in symptoms of nerve damage, so caution is advised. Patients with folic acid deficiency may develop hematological adverse reactions if taking vitamin B12 in a dosage higher than a certain limit. In cases of overdose, symptoms such as nausea, vomiting, hypernatremia, congestive heart failure, and edema may occur. Taking this medicine alongside aldosterone antagonists or triamterene can lead to hyperkalemia, so it requires caution. In case of overdose or lack of improvement after taking the medication for more than a month, one should definitely consult a specialist. This medicine should be taken strictly according to prescribed methods and dosages, and supervision by a guardian is necessary when administering it to children. It may affect blood sugar measurements during urinalysis and can change urine color to yellow, potentially impacting clinical test results. It is advisable to avoid consuming tannin-containing teas such as green tea or black tea during and before/after taking this medicine. This medicine should be stored out of reach of children, in a tightly closed container in a cool, dry place, away from direct sunlight. Moreover, to maintain quality, it is best not to transfer it to other containers.

Serious side effects

Pulmonary edema, edema

Mild side effects

Upper abdominal discomfort, diarrhea, constipation, rash, erythema, nausea, vomiting, loose stool, dermatitis, foul odor during sweating and breathing, hair loss, irritability, gastrointestinal disturbances, digestive issues, upper abdominal pain, hypotension, pulmonary edema, menstrual irregularities (earlier onset or increased volume), prolonged bleeding, sensory neuropathy or neurological symptoms, hematological abnormalities, gastrointestinal symptoms such as nausea and vomiting, hypernatremia, congestive heart failure, edema, hyperkalemia

Drug interactions

This medicine should not be taken with phosphates, calcium salts, oral tetracycline preparations, antacids, or levodopa. If taking oral contraceptives that contain estrogen, aldosterone antagonists, or triamterene, consult with a doctor or pharmacist.

Food interactions

This medicine should be avoided during and before/after taking in combination with tannin-containing teas such as green tea or black tea.

This medicine should be stored in a sealed container to prevent air exposure and kept at room temperature between 1°C and 30°C. Storing it this way helps maintain its effectiveness and prevents degradation.

Appearance

Red oblong film-coated tablets

Package unit

90 tablets/bottle, 180 tablets (90 tablets/bottle x 2)