Medication info

Daewon Megestrol Acetate Suspension

Prescription medicationSuspensionOral
Ingredient · strength
Megestrol Acetate›4000mg / 100mL
Manufacturer / importer
Daewon Pharmaceutical Co., Ltd.
Appearance
A white to cream-colored suspension with an orange flavor and scent contained in a sachet, which easily disperses when shaken.
Packaging
For domestic use: 10mL/sachet X 20, 10mL/sachet X 24, 20mL/sachet X 12, 20mL/sachet X 20 For export: 10mL/sachet X 24, 20mL/sachet X 20, 240mL/bottle
Approval status
Active

MFDS item code 200501627 · Notified 2005.10.31 · Insurance code 671800891,671800893,671800895

Summary

Main use
Treatment of symptoms associated with cancer and AIDS (such as loss of appetite); palliation of cancer (such as breast cancer)
Who takes it
Adults
Adult dose
(Tablets) 1. Breast cancer: Administer megestrol acetate 160 mg daily orally in 4 divided doses (40 mg per dose, 1 tablet per dose, 4 times daily). 2. Endometrial cancer: Administer 40~320 mg daily of this medicine orally in divided doses. An adequate period for assessing the effect of this medicine should be considered by continuing administration for at least 2 months. (Oral suspension) Shake well and take megestrol acetate 800 mg (20 mL) daily. In clinical trials, clinical effects were observed with daily doses of 400~800 mg (10∼20 mL) of this medicine.

Ingredients

Manufacturer
Daewon Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of symptoms associated with cancer and AIDS (such as loss of appetite); palliation of cancer (such as breast cancer)

  • Recurrent breast cancer
  • metastatic breast cancer
  • inoperable breast cancer
  • endometrial cancer
  • appetite loss
  • cachexia
  • unexplained significant weight loss
View approved original text

This medication is used to relieve the symptoms of patients with recurrent, metastatic, or inoperable breast cancer and endometrial cancer. However, it is not suitable as a substitute for surgical or radiation therapy. It is also effective in treating appetite loss, cachexia, and unexplained severe weight loss in cancer or AIDS patients. It helps in the treatment of various cancer-related symptoms.

How to take

Adult dose

(Tablets) 1. Breast cancer: Administer megestrol acetate 160 mg daily orally in 4 divided doses (40 mg per dose, 1 tablet per dose, 4 times daily). 2. Endometrial cancer: Administer 40~320 mg daily of this medicine orally in divided doses. An adequate period for assessing the effect of this medicine should be considered by continuing administration for at least 2 months. (Oral suspension) Shake well and take megestrol acetate 800 mg (20 mL) daily. In clinical trials, clinical effects were observed with daily doses of 400~800 mg (10∼20 mL) of this medicine.

Precautions

This medication can cause very serious harm to the fetus if administered to pregnant women; therefore, it should not be used by women who are pregnant or may become pregnant. Long-term use of this drug may lead to the onset of diabetes or worsening of existing diabetes, and may cause problems with adrenal function, resulting in symptoms such as low blood pressure, nausea, vomiting, dizziness, and weakness. If adrenal insufficiency is suspected, consult a healthcare professional for necessary tests, and in emergencies, administration of medications such as glucocorticoids may be required. People who have had allergic reactions to this medication or its ingredients should not use it, and patients with a history of thrombosis or vascular problems, as well as those with diabetes, should use it with caution. Common side effects may include diarrhea, rash, abdominal bloating, hypertension, weakness, insomnia, nausea, and anemia, while rare reports also indicate heart problems, respiratory distress, neurological disorders, and skin issues. During treatment with this medication, the cause of weight loss should be accurately diagnosed and treated, and long-term use may increase the risk of respiratory infections. Women who may become pregnant must use contraception during treatment, and since this medication can be passed through breast milk and may harm the baby, breastfeeding should be discontinued if nursing. It is not advisable to use this medication in children as safety and efficacy have not been established. There is no specific treatment for overdose, so the prescribed dosage must be strictly adhered to, and caution is needed as this medication is not removed via dialysis. Store in a sealed container to prevent exposure to air or moisture, and place it in a cool place between 15 to 25 degrees Celsius. This way, the medication's effectiveness can be well maintained.

Side effects

Diarrhea

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture, and it is advisable to keep it in a cool place between 15 and 25 degrees Celsius. Storing it this way helps maintain the medication's effectiveness.

Appearance and packaging

Appearance

A white to cream-colored suspension with an orange flavor and scent contained in a sachet, which easily disperses when shaken.

Package unit

For domestic use: 10mL/sachet X 20, 10mL/sachet X 24, 20mL/sachet X 12, 20mL/sachet X 20 For export: 10mL/sachet X 24, 20mL/sachet X 20, 240mL/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.