Afin Tablets (Amlodipine Maleate)

Adult dose

5 mg orally once a day as Amlodipine, and if symptoms do not improve within 2 to 4 weeks, the dose may be increased up to a maximum of 10 mg per day based on the patient's response. Adjust the dosage appropriately according to the symptoms.

This medication should not be used in certain patients. For example, individuals who are allergic to this drug or similar components, pregnant women or women who may become pregnant, and nursing mothers should not take this medication. Additionally, patients in a state of cardiogenic shock, those with severe aortic stenosis or unstable angina, patients within 1 month post-myocardial infarction, individuals with severe liver dysfunction, and patients with severe hypotension should not use this medication. Caution is advised when administering this medication to patients with severely impaired renal function, the elderly, patients with acute heart failure, those in hypertensive crisis, patients with mild to moderate liver dysfunction, individuals with limited left ventricular function, patients with low cardiac reserve, and diabetic patients. When taking this medication, facial flushing or warmth may occur, along with fatigue or edema. Symptoms such as palpitations, dizziness, headaches, nausea, drowsiness, and ankle swelling may also appear, requiring attention. Rarely, symptoms such as dry mouth, excessive sweating, hypotension, fainting, blood abnormalities, liver function abnormalities, skin rashes, or allergic reactions may occur. If these symptoms appear, immediate consultation with a healthcare professional is necessary. This medication should not be abruptly discontinued, as this may worsen symptoms; instead, the dosage should be gradually reduced according to a doctor's instructions, and patients should be careful not to stop taking the medication on their own. It is advisable to take this medication with sufficient water, and due to the possibility of low blood pressure causing dizziness or fatigue, caution should be exercised when driving or operating dangerous machinery. This medication may interact with other drugs; thus, especially avoiding concurrent use with grapefruit juice is recommended. Additionally, it is important to inform a healthcare professional when taking certain antibiotics, antihypertensive medications, or diabetes medications together. Pregnant or nursing women are advised to avoid this medication due to lack of established safety, and its safety and effectiveness in children are also not confirmed. In the elderly, the body's concentration of the drug may increase, so it is best to start with a low dose and closely monitor the condition. In case of overdose, severe hypotension, heart dysfunction, and altered consciousness may occur, necessitating immediate emergency treatment, and appropriate measures should be taken according to healthcare professionals' guidance. Finally, this medication should be stored out of reach of children and should not be transferred to other containers.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme weakness, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urine changes

Mild side effects

• Flushing accompanied by heat sensation
• fatigue
• edema
• palpitations
• dizziness
• headache
• migraine
• weakness
• abdominal pain
• nausea

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. It is also recommended to store it at temperatures between 1 degrees and 30 degrees Celsius at room temperature. Proper storage can help maintain the efficacy of the medication.

Appearance

White octagonal tablet

Package unit

For domestic use: 30 tablets/bottle, 100 tablets (10 tablets/PTP x 10), 300 tablets/bottle, for export: 30 tablets/bottle, 100 tablets/bottle, 100 tablets (10 tablets/PTP x 10)