Cazatan Tablets (Losartan Potassium)

Adult dose

It is recommended to take this medication orally at a dose of 50 mg once daily at the same time, regardless of meals. The maximum blood pressure-lowering effect appears after 3 to 6 weeks of treatment. If the therapeutic effect is insufficient, the dose may be increased to a maximum of 100 mg once daily or divided into two doses per day. In the case of patients with hypertension and type 2 diabetes, the usual dose is typically 50 mg once daily, which may increase depending on blood pressure.

Child dose

For children and adolescents aged 6 years and older weighing 20 kg to less than 50 kg, the recommended dose is 25 mg once daily, and it may be increased up to 50 mg once daily depending on blood pressure response. For those weighing 50 kg or more, the usual dose is 50 mg once daily, which may also be increased depending on blood pressure responses.

This medication can cause serious harm to the fetus if taken during pregnancy, particularly in the second and third trimesters; therefore, women who are pregnant or may become pregnant should not take it. Discontinue immediately if pregnancy is confirmed, and regularly check the fetal condition with ultrasound or other means. This medication should not be administered to patients with severely impaired liver function or certain genetic lactose intolerance. Additionally, those with a history of angioedema or specific kidney diseases should avoid taking it. Elderly patients, those with poor kidney function, and patients with high serum potassium levels should use this medication cautiously, as excessively low blood pressure may lead to issues with the heart or cerebral blood vessels, requiring careful attention. Generally, this medication is well tolerated, but side effects such as dizziness, muscle cramps, cough, and dyspepsia may occur. Rarely, serious side effects like angioedema, liver function abnormalities, renal failure, and hypoglycemia may arise, necessitating immediate consultation with medical personnel if unusual symptoms occur. Regular monitoring of blood pressure, kidney function, and electrolyte levels is necessary while taking this medication to detect any abnormalities. Particularly, caution is required to avoid taking potassium supplements or potassium-containing salt substitutes, as there is a risk of hyperkalemia. Interactions with other antihypertensives, diuretics, non-steroidal anti-inflammatory drugs (NSAIDs), lithium, and others may occur, so it is essential to inform healthcare providers about any other medications being taken. This medication is not recommended for breastfeeding women. If it must be taken, breastfeeding should be discontinued. It is not used in children, especially those under 6 years or those with severely impaired kidney function, as its safety and efficacy have not been established. In cases of overdose, symptoms such as hypotension and bradycardia may occur, requiring immediate treatment, so caution is advised. Keep this medication out of reach of children and do not transfer it to other containers for safety. During treatment, be cautious while driving or operating machinery due to potential dizziness.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanying cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urine

Mild side effects

• Muscle cramps
• low back pain
• leg pain
• dizziness
• congestion
• upper respiratory infection
• sinusitis
• nausea
• diarrhea
• dyspepsia

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. It is recommended to maintain storage temperatures between 1 degree to 30 degrees Celsius at room temperature. This way, the efficacy of the medication can be well preserved.

Appearance

White oval film-coated tablets

Package unit

(Domestic) 30 tablets/bottle, 300 tablets/bottle (Export) 30 tablets (10 tablets/PTP x 3), 100 tablets (10 tablets/PTP x 10)