Maxgrell Tablets (Clopidogrel Hydrogen Sulfate)

Adult dose

○ Adults 1. For patients with ischemic stroke, myocardial infarction, or peripheral arterial disease, administer clopidogrel 75 mg orally once daily. 2. For patients with acute coronary syndrome (unstable angina or non-Q-wave myocardial infarction), start on the day treatment with this medicine is initiated with a loading dose of 300 mg once daily, followed by an oral maintenance dose of 75 mg once daily. Aspirin 75 ～ 325 mg should be administered concomitantly with this medicine once daily. 3. For patients with atrial fibrillation, administer 75 mg of this medicine orally once daily. Aspirin 75 ～ 100 mg should be administered concomitantly with this medicine once daily. This medicine may be administered with or without food.

This medication helps prevent platelets from aggregating, promoting better blood flow. Individuals with reduced function of a specific enzyme (CYP2C19) may experience diminished effects of this medication, and in such cases, it is advised to consult a doctor to adjust the treatment method. Moreover, taking medications that activate certain enzymes alongside this medication may increase the risk of bleeding, so co-administration is not recommended. Patients with allergies to this medication, with active bleeding, severe liver impairment, lactating women, those with lactose intolerance or specific allergies should not take this medication. Patients at high risk of bleeding or those scheduled for surgery should carefully decide on the use of this medication, with a recommendation to discontinue use 5 to 7 days prior to surgery. This medication requires regular monitoring for bleeding or blood abnormalities through blood tests. Caution should be exercised as taking this medication along with other blood coagulation affecting drugs may increase the risk of bleeding. During the course of this medication, the time it takes for bleeding to stop may be longer than usual, so patients should immediately inform a doctor if bleeding is severe or persists. During pregnancy or childbirth, the risk of bleeding may increase, so it is advised to stop using this medication before childbirth or nerve block procedures. In lactating cases, consult a doctor regarding the possibility of this medication being excreted in breast milk. Its safety and efficacy in children have not been established, so use in children is not recommended. For elderly patients, dose adjustment and careful monitoring are necessary as physical functions may decline, increasing the risk of bleeding. In case of overdose, there may be an increased risk of bleeding, and while there is no specific antidote, bleeding may be managed with platelet transfusion. This medication should be kept out of reach of children and should not be transferred to another container.

• Hemorrhage
• gastrointestinal bleeding
• purpura
• contusion
• hematoma
• epistaxis
• hematoma
• hematuria
• intraocular hemorrhage
• intracranial hemorrhage

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage maintains the medication's efficacy and safety.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle