Ophenadine Sustained-Release Tablets 50 mg (Orphenadrine Citrate)

Adult dose

Adults: Administer 100㎎ of orphenadrine citrate orally twice daily (morning and evening). Adjust the dose appropriately according to age and symptoms.

This medication should not be used in patients with glaucoma, pyloric or duodenal obstruction, or exacerbating peptic ulcers. Additionally, it should not be administered to patients with prostatic hypertrophy, bladder neck obstruction, esophageal spasms, or myasthenia gravis. Those with allergic reactions to this medication and nursing women should not take it. As it contains lactose, patients with genetic lactose intolerance or related disorders should also refrain from using this medication. Patients with tachycardia or non-specific heart failure, coronary insufficiency, or arrhythmias should use this medication with caution. Patients with megacolon or acute pulmonary edema also need to be cautious, particularly when administered in injectable form. This medication may first cause symptoms of dry mouth due to its anticholinergic effects. Other side effects may include rapid heartbeat, palpitations, urinary retention and obstruction, blurred vision, dilated pupils, dizziness, headaches, nausea, vomiting, constipation, drowsiness, itching, or rashes. Rarely, serious allergic reactions such as blood disorders or anaphylaxis may occur. Long-term use of this medication requires regular blood, urine, liver, and kidney function tests. Symptoms such as headaches, dizziness, or fainting may occur, so it is advisable to avoid operating dangerous machinery or driving. When used with other medications, interactions may occur, hence caution is warranted. In particular, concurrent use with certain analgesics, Parkinson's disease treatments, some antidepressants, and antipsychotics may amplify side effects. Women who are pregnant or may become pregnant should consult a physician before using this medication, and it should not be used while breastfeeding as it can pass into breast milk. Safety for children has not been established, and it should not be administered to children. Older adults may experience confusion while taking this medication, so dosage adjustment may be necessary.

• dry mouth
• tachycardia
• palpitations
• urinary retention
• urinary obstruction
• blurred vision
• dilated pupils
• increased intraocular pressure
• weakness
• nausea

This medication should be stored in a tightly sealed container to protect it from air and light exposure, and it is best kept at a cool room temperature between 1 to 30 degrees Celsius. This storage method will help maintain the effectiveness of the medication over time.

Appearance

White to off-white sustained-release round tablets

Package unit

30 tablets/bottle, 250 tablets/bottle