L-Rectan Granules (L-Leucine, L-Valine, L-Isoleucine)

Adult dose

Adults take 1 packet (4.226g) orally 3 times a day after meals.

This medication should not be used in patients who are genetically unable to properly metabolize certain amino acids. Administration in such patients may cause serious side effects such as seizures or difficulty in breathing. During the course of taking this medication, gastrointestinal symptoms such as constipation, diarrhea, abdominal bloating, abdominal discomfort, and vomiting may occasionally occur. If these symptoms appear, consider reducing the dosage or temporarily discontinuing the medication. Additionally, it may sometimes affect kidney function and increase blood BUN levels. In such cases, it is also necessary to adjust the dosage or temporarily discontinue use. A metabolic disorder causing elevated blood ammonia levels may occur, so if such symptoms appear, the dosage should be reduced or discontinued. Due to liver dysfunction, there may be elevations in AST, ALT, and bilirubin levels, along with symptoms such as skin rashes, itching, swelling in the face or legs, and fatigue. This medication is only recommended for cirrhotic patients with low serum albumin levels who have sufficient food intake. Patients with diabetes or hepatic encephalopathy should closely monitor their food intake and receive dietary guidance as needed. Those with severe hepatic encephalopathy or significantly elevated total bilirubin levels, or those with severely reduced protein synthesis ability in the liver, should avoid this medication. As this medication contains only branched-chain amino acids, it is important to manage diet to ensure that the patient obtains sufficient protein and calories. Particularly in patients requiring protein restriction, if the minimum amount of protein and calories is not secured, the drug's effectiveness may diminish and nutritional status may worsen. Long-term use may lead to elevated BUN or ammonia levels on blood tests, so regular monitoring is necessary, and overdose may exacerbate nutritional status. If symptoms do not improve after taking for more than 2 months, alternative treatment options should be considered. Elderly patients may have decreased physiological function and be at higher risk for metabolic disorders when taking this medication, so caution is advised. The safety of this medication in pregnant or breastfeeding women has not been established; it should only be administered if the benefits outweigh the risks. The safety in children has not been confirmed, so it is advisable not to use this medication in children. This medication should be stored out of reach of children, and transferring it to another container should be avoided as it may pose a risk of accidents and reduce quality.

Serious side effects

Kidney dysfunction, elevated BUN, severe swelling (including face and limbs).

Mild side effects

• Constipation
• diarrhea
• abdominal bloating
• abdominal discomfort
• nausea
• vomiting
• loss of appetite
• epigastric pain
• thirst
• belching

This medication should be stored in a container that blocks light and allows air circulation, ideally at room temperature between 1°C and 30°C. Storing it this way will help maintain the medication's effectiveness for a longer period.

Appearance

A white granule with a slight sweetness and a lemon scent.

Package unit

4.226g/pack, 30 packs (4.226g/pack x 30), 45 packs (4.226g/pack x 45)