Zanadipin Tablet (Lercanidipine Hydrochloride)

Adult dose

As Lercanidipine Hydrochloride, orally take 5 - 10 mg once daily at least 15 minutes before a meal. The dose can be increased up to 20 mg depending on the patient's symptoms. Dose adjustment should be gradual as it takes about 2 weeks to show the maximum antihypertensive effect. For elderly patients, dosage adjustment is usually not necessary, but caution is needed at the start of treatment. For patients with mild to moderate liver or kidney impairment, special caution is necessary.

This drug should not be administered to certain patients. For example, it should not be taken by individuals allergic to this medication or similar drugs, women who are pregnant or nursing, patients with serious heart problems, and those with severely impaired kidney or liver function. Additionally, some patients need special caution when using this medication. Patients with heart rhythm issues or slightly impaired kidney and liver function, individuals with a history of angina, those who consume alcohol frequently, and the elderly should be cautious when using this medication. Taking this medication may cause symptoms such as facial flushing or swelling of the hands and feet, and side effects such as headache, dizziness, and dyspepsia may occur. Rarely, symptoms such as liver dysfunction, skin rash, and muscle pain may appear, so if any unusual symptoms occur, you should consult a doctor immediately. Abruptly stopping this medication may worsen symptoms, so it is recommended to gradually taper off while monitoring the condition well. Also, dizziness or drowsiness may occur, requiring caution when driving or operating machinery. This medication's efficacy may change when taken with other medications that affect liver metabolism, so if you are currently taking any medications, you must inform your doctor or pharmacist. Especially ant-fungal agents, antibiotics, antiepileptic drugs, and grapefruit juice may alter the blood concentration of this medication, so they should not be taken together. It is safest for pregnant women or those who may become pregnant, as well as nursing mothers, to avoid taking this medication. This drug is not recommended for children and adolescents, and special caution is needed for elderly patients when starting treatment. Overdose can cause serious hypotension and heart problems, so it is essential to stick to the prescribed dosage, and if overdose is suspected, seek medical attention immediately. Finally, this drug should be stored out of reach of children, and transferring it to other containers should be avoided as it may affect the quality of the medication.

Serious side effects

• Chest pain
• angina
• hypotension
• cold sweat
• difficulty breathing

Mild side effects

Facial flushing, peripheral edema, palpitations, tachycardia, headache, dizziness, weakness, fatigue, drowsiness, nervous exhaustion, dyspepsia, nausea, vomiting, abdominal pain, diarrhea, polyuria, frequent urination, gingival hypertrophy, rash, muscle pain, tremors, insomnia, dry mouth, hand numbness, coughing, abdominal distension, erectile dysfunction, hypotension, arrhythmia, cold sweat, skin tingling, premature contractions, tongue rigidity, increased ventricular premature beats (VPB), gastrointestinal disturbances

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is best to keep it in a cool place, ideally at room temperature between 1 degree and 30 degrees.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle