Memantine Tablets 10 mg (Memantine Hydrochloride)

Adult dose

The maximum daily dose is 20 mg, and it should be increased by 5 mg per week over the first 3 weeks. In the first week (days 1-7): administer 5 mg once daily for 7 days. In the second week (days 8-14): administer 10 mg once daily (5 mg twice a day) for 7 days. In the third week (days 15-21): administer 15 mg once daily (10 mg in the morning and 5 mg in the evening) for 7 days. From the fourth week onward: administer 20 mg once daily (10 mg twice a day).

This medication should not be used in patients who are allergic to any component of this medication or in patients with severe liver or kidney dysfunction. Care should be taken when using this medication in patients with epilepsy, those who have experienced seizures, or those who are prone to seizures. Additionally, co-administration with NMDA antagonists such as amantadine, ketamine, or dextromethorphan may increase side effects, and should be avoided. Patients with changes in urine acidity (pH) or dietary habits that may increase urine acidity should be monitored carefully. There is insufficient clinical data in patients with myocardial infarction, heart failure, or uncontrolled hypertension, so administration should be cautious. While taking this medication, side effects such as dizziness, headache, constipation, drowsiness, and hypertension may occur. Mental confusion, hallucinations, and psychotic symptoms may also occur rarely, so caution is required. This medication may interact with other substances, so it is important to consult with a doctor or pharmacist if taken alongside antipsychotic medications, muscle relaxants, anticoagulants, etc. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of using this medication, and discontinuation of breastfeeding is recommended while using it. Safety and efficacy in children and adolescents under 18 years of age have not been established. In case of overdose, serious symptoms such as coma, hallucinations, and seizures may occur, so immediate medical attention is necessary. This medication can affect the central nervous system, so care should be taken when driving or operating machinery. Finally, this medication should be kept out of reach of children and should not be transferred to other containers for safety.

Serious side effects

• Seizures
• heart failure
• venous thromboembolism
• shortness of breath
• headache (including severe headache)
• hallucinations
• psychotic reactions
• confusion
• gait abnormalities
• severe dizziness

Mild side effects

• Dizziness
• headache
• constipation
• drowsiness
• hypertension
• confusion
• hallucinations
• psychotic reactions
• balance disorders
• gait abnormalities

This medication should be stored in a tightly closed container that is well-ventilated and kept at room temperature between 1 and 30 degrees Celsius. Storing it this way maintains the drug's effectiveness and prevents degradation.

Appearance

White, rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle