Medication info
Adiresin Capsule (Diacerein)

Adiresin Capsule (Diacerein)

Prescription medicationHard capsuleOral
Ingredient · strength
Diacerein›50mg / 1 capsule
Manufacturer / importer
IYON Pharmaceutical Co., Ltd.
Appearance
Hard capsule with a brown-yellow content in the upper part - yellow, lower part - light yellow
Packaging
30 capsules/bottle, 500 capsules/bottle
Approval status
Active

MFDS item code 200500237 · Notified 2005.04.08 · Insurance code 658600570

Summary

Main use
Treatment of osteoarthritis
Who takes it
Adults
Adult dose
Adults: Administer 50∼100mg of diacerein orally in 1∼2 divided doses after meals. Adjust the dose appropriately according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily is recommended for the first 2-4 weeks, followed by 50mg twice daily.

Ingredients

Manufacturer
IYON Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of osteoarthritis

  • Osteoarthritis
  • hip joint arthritis
  • knee joint arthritis
  • arthrosis
  • degenerative joint disease
View approved original text

Degenerative arthritis of the hip joint and knee joint, namely arthrosis, is a disease in which the joint cartilage gradually wears away, causing pain and limited movement. This medication is used to relieve the symptoms of such osteoarthritis and improve joint function.

How to take

Adult dose

Adults: Administer 50∼100mg of diacerein orally in 1∼2 divided doses after meals. Adjust the dose appropriately according to symptoms. For patients with a history of loose stools or diarrhea, an initial dose of 50mg once daily is recommended for the first 2-4 weeks, followed by 50mg twice daily.

Precautions

This medication should not be used in patients with inflammatory bowel disease, intestinal obstruction syndrome, or unexplained abdominal pain. Additionally, patients with allergies to this medicine, its ingredients, or Rhein compounds should not take it. This medication should not be used by individuals with liver disease or those who have had liver disease in the past, as well as children under 15 years of age. This medication contains lactose, so patients with genetic issues such as lactose intolerance or galactose intolerance, Lapp lactase deficiency, and glucose-galactose malabsorption should not take it. Patients with a history of small intestine or colon diseases, women who are pregnant or breastfeeding, and elderly individuals over 65 should use this medication cautiously, and especially in the elderly, the dosage should be reduced. This medication contains a pigment called Yellow No. 5, so those sensitive to this component or with a history of allergies should be cautious. During use, gastrointestinal symptoms such as diarrhea, loose stools, and abdominal pain may occur, and long-term use could lead to serious problems such as gastrointestinal bleeding, ulcers, or perforation. If severe diarrhea occurs, dehydration or electrolyte imbalance may ensue, so if these symptoms appear, consult a physician immediately. Skin reactions such as itching, rashes, and eczema can also occur frequently. There is a possibility of altered liver function, so if there are signs of elevated liver enzymes or liver damage, stop taking the medication and follow your doctor's instructions. When using this medication long-term, it is essential to follow the doctor's instructions, and if diarrhea occurs, stop taking it and consult with a physician. Taking this medication with antacids or medications containing calcium, magnesium, or aluminum may hinder its absorption, so it's advisable to take them at least 2 hours apart. Taking it along with diuretics may enhance diuretic effects, increasing the risk of dehydration or hypokalemia, so caution is advised. Moreover, when combined with cardiac glycosides, the risk of arrhythmias increases, so it should be taken after consulting a physician. Pregnant or breastfeeding women should avoid using this medication as it may affect the fetus or newborn. In case of overdose, severe diarrhea may occur, and appropriate treatment such as electrolyte replenishment may be necessary.

Side effects

  • Diarrhea
  • loose stools
  • abdominal pain
  • gastrointestinal disorders
  • bleeding
  • ulcers
  • perforation
  • pigmentation of the rectal mucosa
  • dehydration
  • fluid and electrolyte imbalance
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  • itching
  • rash
  • eczema
  • elevated serum liver enzymes
  • hypokalemia
  • symptoms of liver damage
  • severe diarrhea

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air or moisture exposure. It is advisable to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Hard capsule with a brown-yellow content in the upper part - yellow, lower part - light yellow

Package unit

30 capsules/bottle, 500 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.